Protein Alignment tll and nr1h5

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001107159.1
• Gene: nr1h5 / 100135016
• XenbaseID: XB-GENE-486722
• Length: 513
• Species: Xenopus tropicalis
• Alignment Length: 440
• Identity: 104/440 - (23%)
• Similarity: 164/440 - (37%)
• Gaps: 106/440 - (24%)

  Fly    11 MDQKYNSV---RLSPAASSRILYHVP-CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCK 71
            :|:.|.::   |:| .||.|:..|.. |.||.|.:||.||....|:||.|||:|||.::..|.||
 Frog   105 VDEVYPTMKRPRVS-HASIRMKGHEELCVVCGDKASGYHYNALTCEGCKGFFRRSITKNAVYRCK 168

  Fly    72 SQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAGEMPQ 136
            :  .|.|.:|...|.:|:.|||:||..|||..:.:..|...::..||::..
 Frog   169 N--GGHCEMDMYMRRKCQECRLKKCKAVGMLAECLLTEVQCKSKRLRKNCK-------------- 217

  Fly   137 IPAEILMNTAALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPR---VPHHPVH 198
                  .|.:.|:   .|.:...|...|      |:::...|...::..:|:...   :.|  :.
 Frog   218 ------QNNSMLS---NVKVEDEGSDSR------HVSSTTKPTKLSSQPELTAEECKLIDH--IV 265

  Fly   199 QGHHGFFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLL 263
            ..|.....|    ::.|.........|.....|..|.|..|:...|.:.|.:..|..|...||:.
 Frog   266 TAHQKCGIP----LDDLKIFLEESADPEEIFYHFSEAAVLHVQAFVEFTKRLPGFEMLDHEDQIA 326

  Fly   264 LLEESWKEFFILAMAQ-YLMPMNFAQL-----LFVYESENANREIMGMVTR------EVHAFQEV 316
            ||:.|..|..:|..|| |.:|:....|     |..|.:.:.:...:....|      |.|:.|:|
 Frog   327 LLKGSTVEAMLLRSAQIYNLPVMGCSLQTTEGLARYPNHSVDFSQIQEFDRCPLYSLEAHSHQDV 391

  Fly   317 ------------------LNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGS 363
                              ...:..||:...||..|.|:::|....|
 Frog   392 STSTADLTEEFITPLFKFFRSMGSLNVTEAEYALLSAVTVFFSDRP------------------- 437

  Fly   364 PNSSASAESRGLLES-GKVAAMHNDARSALHNYIQRTHPSQPMRFQTLLG 412
                       ||:: ..|..:.......||.|.:..||..|..|..|:|
 Frog   438 -----------LLQNKPHVEKLQEPLLGILHKYSKLYHPEDPQHFARLIG 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	37/92 (40%)
		NR_LBD	215..436	CDD:416257	49/229 (21%)
nr1h5	NP_001107159.1	NR_DBD_FXR	128..211	CDD:143520	34/84 (40%)
		NR_LBD	256..506	CDD:386099	52/257 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910