DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tll and atxn7

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_012815985.1	Gene:	atxn7 / 100127691	XenbaseID:	XB-GENE-956283	Length:	905	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	73/308 - (23%)
Similarity:	106/308 - (34%)	Gaps:	89/308 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 PGVPMPMP---GLPQRAGHHPAHMAAFQPPPSAAAVLD---------------LSVPRVPHHPVH 198
            |.:|..:|   |.|....|...|......|..||..:.               .:..|.......
Frog    21 PRLPYKLPPVSGGPAPPAHSRTHSPRQASPGPAAERMSERAEDDVTGEQQQRRAAAGRQQRRQQQ 85

  Fly   199 QGHHGFFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLL 263
            ||.    |.:||.|.|...|...|:|..|..:           ...:|:::|:.       ..|.
Frog    86 QGE----SSSAAAMAAGGDRTSLPSPGAMLGQ-----------PWAHWVEAVKL-------HGLE 128

  Fly   264 LLEESWKEFFILAMAQYLMPMNFAQLLFVYESENANRE---IMGMVTREVHAFQEVLNQLC-HLN 324
            .|||||||.....                 ||...:||   |.|:..    |:.|....:| |.|
Frog   129 ELEESWKECDKKR-----------------ESMRLSREDMAIFGLCP----AYDEFYLVMCSHCN 172

  Fly   325 ------IDSTEYECLRAISLFRKSP--PSASSTEDL----ANSSILTGSGS-----PNSSASAES 372
                  ...:.||  |..|...|:|  |.:|||..|    ::.:..:|.||     |:|.:||.|
Frog   173 QVIKPQAFQSHYE--RRHSSINKTPVTPPSSSTNSLYSTVSSKTKPSGGGSCSSTRPSSGSSASS 235

  Fly   373 RG-LLESGKVAAMHNDARSALHNYIQRTHPSQPM-RFQTLLGVVQLMH 418
            .. |::|.|.......:..::|. :|  |...|. :..|....|:.||
Frog   236 NSKLMKSPKDKLPIGGSNKSVHP-VQ--HSKAPQEKIMTPSVKVEKMH 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537
tll	NP_524596.1	NR_LBD	215..436	CDD:416257	55/227 (24%)
atxn7	XP_012815985.1	SCA7	347..412	CDD:369807
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X118
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000