Protein Alignment tll and nr2f1

DIOPT Version :10

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: XP_012815199.1
• Gene: nr2f1 / 100101681
• XenbaseID: XB-GENE-480018
• Length: 411
• Species: Xenopus tropicalis
• Alignment Length: 420
• Identity: 131/420 - (31%)
• Similarity: 202/420 - (48%)
• Gaps: 100/420 - (23%)

  Fly    31 HVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRK 95
            |:.|.||.|.|||||||.:.|:||..|||||:||:..|.|::.:.  |.:|:.|||||:.|||:|
 Frog    71 HIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRN--CPIDQHHRNQCQYCRLKK 133

  Fly    96 CFEVGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAGEMPQIPAEILMNTAALTGFPGVPMPMPG 160
            |.:|||.::|||.                       |.||  |.:......|||.  |.|:
 Frog   134 CLKVGMRREAVQR-----------------------GRMP--PTQPNPGQYALTN--GDPL---- 167

  Fly   161 LPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTPP 225
                .||  .:::.:         :.|.:...|:            ||:.|    .::.:.|. .
 Frog   168 ----NGH--CYLSGY---------ISLLLRAEPY------------PTSRY----GSQCMQPN-N 200

  Fly   226 LMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMPMNFAQLL 290
            :|..|:|.|.||..||..|.|.:::..|.:|.:.||:.||..:|.|.|:|..||..||::.|.||
 Frog   201 IMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLL 265

  Fly   291 F---VYESE-NANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTED 351
            .   ::.|. :|:|.:..|  ..:..|||.:.:|..|::||.||.||:||.||
 Frog   266 AAAGLHASPMSADRVVAFM--DHIRIFQEQVEKLKALHVDSAEYSCLKAIVLF------------ 316

  Fly   352 LANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPMRFQTLLGVVQL 416
                             ::::.||.::..:.::...::.||..|::..:|:||.||..||..:..
 Frog   317 -----------------TSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPS 364

  Fly   417 MHKVSSFTIEELFFRKTIGDITIVRLISDM 446
            :..|||..||:|||.:.:|...|..||.||
 Frog   365 LRTVSSSVIEQLFFVRLVGKTPIETLIRDM 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	42/85 (49%)
		NR_LBD	215..436	CDD:472173	67/224 (30%)
nr2f1	XP_012815199.1	NR_DBD_COUP_TF	74..146	CDD:143516	40/73 (55%)
		NR_LBD_COUP-TF	172..407	CDD:132746	78/280 (28%)