Protein Alignment tll and nr1d1

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001093675.1
• Gene: nr1d1 / 100101679
• XenbaseID: XB-GENE-478094
• Length: 522
• Species: Xenopus tropicalis
• Alignment Length: 478
• Identity: 125/478 - (26%)
• Similarity: 190/478 - (39%)
• Gaps: 122/478 - (25%)

  Fly    19 RLSPAASSRILYHVP-----CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLC 78
            |:||:.:|..:..:.     ||||.|.:||.|||::||:||.|||:|||:::.||. |..|...|
 Frog    95 RVSPSKTSSSITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYK-KCLKNETC 158

  Fly    79 VVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLR----RHMAMYKDAMMGAGEMPQIP- 138
            .:.:.:||:|:.||.|||..|||::|||:..|.|:....|    .|.||...|....|....||
 Frog   159 SIVRINRNRCQQCRFRKCLSVGMSRDAVRFGRIPKREKQRMLAEMHSAMNHIASGHFGRRSPIPL 223

  Fly   139 -------------AEILMNTAALTGFPGVPMPMP-GLPQRAGHHPAHMAAFQPP--PSAAAVLD- 186
                         :..||.||        |...| .||.....:|..:.   ||  ||...:.|
 Frog   224 QPHQQQQQQLHPSSSPLMGTA--------PCHSPTSLPDAYSQYPQQLT---PPRSPSPEHMDDV 277

  Fly   187 LSVPRVPH-------------------------HPVHQGHHGFFSPTAAYMNALATRALPPTPPL 226
            :|...:.|                         |.....|.......|..||||....     |:
 Frog   278 ISQVSMAHRQIFVYANDKVNKKTSWDHPQPCWSHDTEDSHGNHNIRLACPMNALHRGG-----PV 337

  Fly   227 MAAEHIKE------TAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMPMN 285
            .:.:.:.|      |.|  :.:.|.:.:.:..|.:|...||:.||:....|         ::.:.
 Frog   338 RSVQEVWEDFSLSFTPA--VREVVEFARHIPGFKDLTQNDQVTLLKAGTFE---------VLMVR 391

  Fly   286 FAQLLFVYESENANREIMGMV--TREVHA--FQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSA 346
            ||.|...  .|::.|.:.|..  ..|:||  ..|:|:.:...:      |.|.::||
 Frog   392 FASLFDA--REHSLRFLSGATYSLPELHAMGMGELLSSMFDFS------EKLSSLSL-------- 440

  Fly   347 SSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPMRFQTL- 410
             |.|:|...:.|.       ..||:..|:..|..|..:......||.:.|.:..|:...||..|
 Frog   441 -SQEELGIFTALV-------LVSADRSGMENSSLVEQLQETLIRALRSLILKNSPNDTSRFTKLL 497

  Fly   411 -----LGVVQLMH--KVSSFTIE 426
                 |..:..||  |:.||.::
 Frog   498 LRLPDLRTLNNMHSEKLLSFRVD 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	42/96 (44%)
		NR_LBD	215..436	CDD:416257	50/230 (22%)
nr1d1	NP_001093675.1	NR_DBD_REV_ERB	110..198	CDD:143540	41/88 (47%)
		NR_LBD	331..519	CDD:299703	50/227 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910