DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tll and nr0b1

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001076416.1	Gene:	nr0b1 / 100001692	ZFINID:	ZDB-GENE-070130-1	Length:	264	Species:	Danio rerio

Alignment Length:	224	Identity:	51/224 - (22%)
Similarity:	92/224 - (41%)	Gaps:	39/224 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   234 ETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLM---------PMNFAQL 289
            :.|:..|.|.:.::|:|..|.|||..||..|:...|....:|.|||..:         |....::
Zfish    67 KAASAVLVKTLKFVKNVPCFRELPADDQHTLVRSGWAPLLVLGMAQDRIDFETSETQEPSMLQRI 131

  Fly   290 LFVYESENANREIMGMVT-REVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLA 353
            |...:.:..|:...|.|. .:|...:..|.:...|:|.:.||..|:...||         ..|:|
Zfish   132 LTSGQDKQDNQSHNGGVALTDVQGIKMFLRKCWGLDISTKEYAYLKGAILF---------NPDVA 187

  Fly   354 NSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPMRFQTLLGVVQLMH 418
                                ||.....:.|:.::|..||:.|::..|.....||..|...:.::.
Zfish   188 --------------------GLQCQHYIQALQSEANQALNEYVKMIHRGDSARFAKLFLALSMLR 232

  Fly   419 KVSSFTIEELFFRKTIGDITIVRLISDMY 447
            .:::..:..|||:..||.:.:..|:.:|:
Zfish   233 SINANVVAGLFFKPVIGAVNMEELLLEMF 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537
tll	NP_524596.1	NR_LBD	215..436	CDD:416257	48/211 (23%)
nr0b1	NP_001076416.1	NR_Repeat	15..57	CDD:290753
nr0b1	NP_001076416.1	NR_LBD_Dax1	44..259	CDD:132764	50/220 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910