Protein Alignment cindr and sh3d21

DIOPT Version :9

• Sequence 1: NP_001263129.1
• Gene: cindr / 43654
• FlyBaseID: FBgn0027598
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: XP_005158368.1
• Gene: sh3d21 / 641492
• ZFINID: ZDB-GENE-051120-57
• Length: 497
• Species: Danio rerio
• Alignment Length: 781
• Identity: 165/781 - (21%)
• Similarity: 237/781 - (30%)
• Gaps: 362/781 - (46%)

  Fly    13 YAAKEPDELDLQKGAIIHRI-KQMPGGWWQGTLKASGVTGMFPDNFVRVLESGVSSNGNGTTGSG 76
            :.|..||||.:..|.|:..: |....||.:|.|:  |..||||.|||:.:...:..:.|....|
Zfish     9 FEATMPDELTVHVGDIVKNVSKAKEEGWLEGDLR--GKRGMFPGNFVKEVPVYLIGDSNREPRS- 70

  Fly    77 DHIEVGTAVQLRDKSATSNRRCKVIYSYTQVNDDELTLAVGDVIEFLGEVEEGWWRGRLRSKVGV 141
                    ::...|:....|:|:|::.|...::|||.|.||:.||.|.|:|:|||.|:..:::|.
Zfish    71 --------IRKTKKTTVQTRKCEVVFPYVPTHEDELQLLVGETIEILREIEDGWWMGKKNNQIGA 127

  Fly   142 FPSNFVQHI-EPSPVLASKRPPTIGATV-------TTSALTSKAANVANVAATATVPTGGAVPPA 198
            ||||||:.| .||...|..||...|:..       ...:|..|.:||
Zfish   128 FPSNFVKEIFVPSKDDAKARPKLSGSVFGKEGKLQQRPSLRKKTSNV------------------ 174

  Fly   199 STSISTSTTKQATKSRATAAAAASAPAEPAAIVSGSGAAAGGGAAAAVPMLPPKPQREFCRVEFP 263
                                                                    :|.|:|.|.
Zfish   175 --------------------------------------------------------KECCQVMFD 183

  Fly   264 YAPQNDDELELKVDDIIAVISTELPDKGWWKGEIRGKVGVFPDNFVKMLAPSEATAAPPLPRPRP 328
            ||...:|||.||..|:|.||:....|.|||:||:.|:.|.|||||| ||.|:|.
Zfish   184 YAAVAEDELNLKKGDVITVINKSTEDDGWWEGEVNGRRGFFPDNFV-MLIPAET----------- 236

  Fly   329 RTRPGMGGTGAGSGSGIIDGVRTPRRTQRGGSFEFLGARMASFITTIFAPINEPPSATQITQNQR 393
                                      .|.|.:.:              ||:..  .:.:.::||.
Zfish   237 --------------------------LQTGNAGQ--------------APVRS--GSKKDSENQM 259

  Fly   394 KVSNTASTTSHMTTTNSSNSSTTSVTTQQQKEQIGGSSSTTSKVYIKKTGSSSNSTTSSTTTASS 458
            .|.:             .|||.|...|:             :|:
Zfish   260 PVMD-------------QNSSDTKPKTE-------------TKI--------------------- 277

  Fly   459 SAGRKESFGSRDSLNDILSETGLPTGNVAAQRKSLENKNLDLTKPPGVGASVSIGQQRSSTSSAT 523
                 :...::|..:|       |.|.:         |...|.|||.....|.
Zfish   278 -----DKPDNKDFRSD-------PPGKI---------KLPGLHKPPVPPPPVK------------ 309

  Fly   524 TSSATTVATGLTSSSVSKSMENMLDEKVKSPPPPVLSKKPSVPLK----KTPTGGVPMTGNLLGG 584
                        ..::.|..:| .:|..|.||||....|....:|    |||
Zfish   310 ------------DKAIKKDPKN-AEEPQKQPPPPSPVHKEVKDIKEVKDKTP------------- 348

  Fly   585 KKKNTEGKLTTAVSHDLADGLAASKMLSGANQLPESGAAGNVVIRRAATIAVEDTDFDRVERASI 649
                           |..||:..|.                                   |:.|.
Zfish   349 ---------------DQFDGVDVSS-----------------------------------EKLSH 363

  Fly   650 LTDMRQGRVKAPKRRPPSAAINVLGESNNNSVYVNGSGMSGSGGAGSASELSEDGGAGGKTSDDN 714
            .|   ..|.|.|:||||:|....:                                 .|....|.
Zfish   364 PT---ANRAKPPQRRPPTALATAI---------------------------------QGPAETDC 392

  Fly   715 STGEEPQLAKPK--PREWEKKKAPWMEELKASQVTRKKTSPS---------VEPRGASVAERTSK 768
            |...|.:...|:  |...|.:.||       |..|...||||         |:..|||:|...::
Zfish   393 SKPSEEKDGAPQHIPEATESQSAP-------SSKTEPVTSPSKIQTDSRSAVQEDGASLASVLTE 450

  Fly   769 L 769
            |
Zfish   451 L 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cindr	NP_001263129.1	SH3_CD2AP-like_1	6..60	CDD:212806	20/47 (43%)
		SH3_CD2AP-like_2	97..149	CDD:212807	25/51 (49%)
		SH3_CD2AP-like_3	258..310	CDD:212808	27/51 (53%)
sh3d21	XP_005158368.1	SH3_CD2AP-like_1	2..55	CDD:212806	20/47 (43%)
		SH3_CD2AP-like_2	83..135	CDD:212807	25/51 (49%)
		SH3_D21-like	177..231	CDD:213018	28/54 (52%)
		Tmemb_cc2	<407..>494	CDD:287269	16/52 (31%)
		LCD1	449..>483	CDD:286837	1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574454
Domainoid	1	1.000	72	1.000	Domainoid score	I9266
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1577081at2759
OrthoFinder	1	1.000	-	-		FOG0002275
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14167
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1165
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950