Protein Alignment cindr and sh3d21

DIOPT Version :9

• Sequence 1: NP_001263129.1
• Gene: cindr / 43654
• FlyBaseID: FBgn0027598
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: XP_004911622.2
• Gene: sh3d21 / 100145355
• XenbaseID: XB-GENE-5889544
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 696
• Identity: 155/696 - (22%)
• Similarity: 254/696 - (36%)
• Gaps: 212/696 - (30%)

  Fly     8 IVEYEYAAKEPDELDLQKGAIIHRIKQ-MPGGWWQGTLKASGVTGMFPDNFVRVLESGVSSNG-- 69
            :|..::..:..|||.::.|.:|..:|: ...||.:|.||  |..|.||..||:.:.....::.
 Frog     8 LVLVDFKGQLDDELKIKAGDVIQNVKKTAEEGWLEGELK--GKRGFFPQMFVKEIPPFFLNDSAQ 70

  Fly    70 -------------------NGTTGSGDHIEVGTAVQLRDKSATSNRRCKVIYSYTQVNDDELTLA 115
                               .|.......|:.|.|...:.|     |.|:|.|:|...:.|||.|:
 Frog    71 RYPRSIRKPNASMVPQIPQEGPPEKQTPIDDGYARVNKKK-----RWCRVEYAYKASSADELELS 130

  Fly   116 VGDVIEFLGEVEEGWWRGRLRSKVGVFPSNFVQHIEPSPVLASKRPPTIGATVTTSALTSKAANV 180
            ||:|.:.|.|:|:|||.|:....||.||||||:.:...|   |::.|.:          ||.|..
 Frog   131 VGEVFQVLEEIEDGWWLGKKGEAVGAFPSNFVKEVPEPP---SEKIPEL----------SKNAKK 182

  Fly   181 ANVAATATVPTGGAVPPASTSISTSTTKQATKSRATAAAAASAPAEPAAIVSGSGAAAGGGAAAA 245
            .               ||...|:.|..::....:...:...:...|.::
 Frog   183 R---------------PAMMDINFSAKEEEKSKQEDKSVPENQSKEDSS---------------- 216

  Fly   246 VPMLPPKPQREFCRVEFPYAPQNDDELELKVDDIIAVISTELPDKGWWKGEIRGKVGVFPDNFVK 310
                 |...:|:|||.|.|.|...|||.||..|:|.:||.|..|:|||:||..||.|:||||||.
 Frog   217 -----PPHAKEYCRVMFDYKPFLPDELALKKGDVILLISKETGDEGWWQGEHNGKTGLFPDNFVL 276

  Fly   311 MLAPSEATAAPPLPR-----PRPRTRPGMGGTGAGSGSGIIDGVRTPRRTQRGGSFEFLGARMAS 370
            ::.|........||.     ..|.|:         |...|:|  :.|...::..
 Frog   277 IIPPDMQIKTNKLPTRTSTIKSPVTK---------SDLNIMD--KKPHEVKKPA----------- 319

  Fly   371 FITTIFAPINE-PPSATQITQNQRKVSNTASTTSH----------MTTTNSSNSSTTSVTTQQQK 424
                  |.:|: .|:.|:..|.:.|...:...|:.          :..:...|:...:..:.:..
 Frog   320 ------AEVNKHEPTTTKKGQREPKTDLSPKVTNQPGKKAAPPPPVPKSAKHNTGPLNKPSTEAG 378

  Fly   425 EQIGGSSSTTSKVYIKKTGSSSNSTTSSTTTASSSAGRKESFGSRDSLNDILSETGLPTGNVAAQ 489
            |.:..||        |::.:......||...|..:|.|.:..|.|           ||.|.|.:.
 Frog   379 EDVNHSS--------KESNTLDGLRVSSMKLAHPTADRPKMMGKR-----------LPKGKVTSP 424

  Fly   490 RKSL----ENKNLDLTKPPGVGASVSIGQQRSSTSSATTSSATTVATGLTSSSVSKSMENMLDEK 550
            .|.:    :.||                 :....|.:..|||..                  |.:
 Frog   425 EKPISESDDKKN-----------------EEQVNSHSKVSSAPK------------------DPR 454

  Fly   551 VKSPPPPVLSKKPSVPLKKTPTGGVPMTGNLLGGKKKNTEGKLTT--AVSHDLADGLAASKMLSG 613
            :.:.|.|    .|| |.|.:|..  |:..:.:...:|..:...::  ::..|||..:|:.|.:.
 Frog   455 IPTTPSP----SPS-PTKTSPLS--PLATSTVKQSQKTADNHASSVQSLQEDLAAEIASIKFMM- 511

  Fly   614 ANQLPESGAAGNVVIRRAATIAVEDTDFDRVERASILTDMRQGRVK 659
                        .::|...|..:||          |.:::.:.|.|
 Frog   512 ------------ELLRNKHTKDMED----------IRSELNEERTK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cindr	NP_001263129.1	SH3_CD2AP-like_1	6..60	CDD:212806	18/52 (35%)
		SH3_CD2AP-like_2	97..149	CDD:212807	26/51 (51%)
		SH3_CD2AP-like_3	258..310	CDD:212808	30/51 (59%)
sh3d21	XP_004911622.2	SH3	6..59	CDD:418401	18/52 (35%)
		SH3_CD2AP-like_2	112..164	CDD:212807	26/51 (51%)
		SH3_D21-like	223..277	CDD:213018	31/53 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1577081at2759
OrthoFinder	1	1.000	-	-		FOG0002275
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1165
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010