DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and Prkcq

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	NP_001263650.1	Gene:	Prkcq / 85420	RGDID:	620968	Length:	707	Species:	Rattus norvegicus

Alignment Length:	419	Identity:	128/419 - (30%)
Similarity:	201/419 - (47%)	Gaps:	95/419 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   684 KVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAM 748
            |...|.:.::.:     |:.|..::|   |:|.  |:..|.:|.|:||:|.| ::...:...:|:
  Rat   355 KTAQPPEPEVNL-----QRASLQLKL---KIDD--FILHKMLGKGSFGKVFL-AEFKRTKQFFAI 408

  Fly   749 KTLRKADVLKRNQVAHVKAERDILAEA-DNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKL 812
            |.|:|..||..:.|.....|:.:|:.| ::.::..::.:||.|:||:|||:|:.|||||..:...
  Rat   409 KALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSC 473

  Fly   813 GIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYY 877
            ..|:...|.||.||:...:..:|..|.::||:|.||||:|||||||:.|||:|
  Rat   474 HKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLDRDGHIKIADFGMC------------ 526

  Fly   878 QENGNHSRQDSMEPWEEYSEN--GPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQ 940
                              .||  |...|               ::..|||:|||||:|....|..
  Rat   527 ------------------KENMLGDAKT---------------NTFCGTPDYIAPEILLGQKYNH 558

  Fly   941 LCDYWSVGVILYEMLVGQPPFLANSPLETQQKV-------INWEKTLHIPPQAELSREATDLIRR 998
            ..|:||.||:|||||:||.||......|....:       ..|           |.|||.||:.:
  Rat   559 SVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW-----------LEREAKDLLVK 612

  Fly   999 L-CASADKRLGKSVDEVKSHDFFKGIDFADMRKQK--APYIPEIKHPTDTSNFDPVDPEKLRSND 1060
            | ....:||||...| ::.|..|:.|::.::.:::  .|:.|::|.|.|.||||    ::..|..
  Rat   613 LFVREPEKRLGVRGD-IRQHPLFREINWEELERKEIDPPFRPKVKSPYDCSNFD----KEFLSEK 672

  Fly  1061 STMSSGD-----DVDQNDRTFHGFFEFTF 1084
            ..:|..|     .:|||     .|..|:|
  Rat   673 PRLSFADRALINSMDQN-----MFSNFSF 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	118/378 (31%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	101/311 (32%)
Prkcq	NP_001263650.1	C1_1	160..212	CDD:278556
		C1_1	232..284	CDD:278556
		STKc_nPKC_theta	374..704	CDD:270770	124/395 (31%)
		S_TKc	380..634	CDD:214567	101/311 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910