Protein Alignment wts and TPK3

DIOPT Version :10

• Sequence 1: NP_733403.1
• Gene: wts / 43651
• FlyBaseID: FBgn0011739
• Length: 1105
• Species: Drosophila melanogaster
• Sequence 2: NP_012755.1
• Gene: TPK3 / 853688
• SGDID: S000001649
• Length: 398
• Species: Saccharomyces cerevisiae
• Alignment Length: 370
• Identity: 122/370 - (32%)
• Similarity: 193/370 - (52%)
• Gaps: 70/370 - (18%)

  Fly   696 RKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNH---LYAMKTLRKADVL 757
            :.||..::::      .|...|.|..|:.:|.|:||.|.|:    .|||   .||:|||:|..::
Yeast    71 KPMLQYRDTS------GKYSLSDFQILRTLGTGSFGRVHLI----RSNHNGRFYALKTLKKHTIV 125

  Fly   758 KRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARF 822
            |..||.|...||.:|:...:.::::::.:|||...::.|||||.||:|.|||.|...|...:|:|
Yeast   126 KLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKF 190

  Fly   823 YIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQD 887
            |.|||..|::.:|....|:||:||:|||:|::||||:||||.         :||..:
Yeast   191 YAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGF---------AKYVPD-------- 238

  Fly   888 SMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILY 952
                                         :.::|.|||:||||||:....|.:..|:||.||::|
Yeast   239 -----------------------------VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIY 274

  Fly   953 EMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCA-SADKRLG---KSVDE 1013
            |||.|..||..::.::|.:.::|.|  |..||  ....:|.||:::|.. ...:|||   ...::
Yeast   275 EMLAGYTPFYNSNTMKTYENILNAE--LKFPP--FFHPDAQDLLKKLITRDLSERLGNLQNGSED 335

  Fly  1014 VKSHDFFKGIDFADM--RKQKAPYIPEIKH-PTDTSNFDPVDPEK 1055
            ||:|.:|..:.:..:  |..:.||.|.|:. ..|||.||....|:
Yeast   336 VKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEE 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	MobB_LATS1	644..718	CDD:439273	3/21 (14%)
		STKc_LATS	717..1078	CDD:270749	119/349 (34%)
TPK3	NP_012755.1	STKc_PKA_like	86..376	CDD:270732	118/343 (34%)