DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and KCC4

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	NP_009907.2	Gene:	KCC4 / 850334	SGDID:	S000000529	Length:	1037	Species:	Saccharomyces cerevisiae

Alignment Length:	363	Identity:	91/363 - (25%)
Similarity:	156/363 - (42%)	Gaps:	85/363 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   725 IGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRN-------QVAHVKAERDI----LAEADNN 778
            :|.|:.|:|.| ::.:.:.|..|:|.:.|: :...|       .|.....||:|    |....|
Yeast    27 LGFGSTGKVQL-AQHERTGHRTAVKVISKS-IFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPN- 88

  Fly   779 WVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRD 843
             |:.||..::..:|||.:::|...|:|.:||:..|...|..|.....::...:...|.:|.:|||
Yeast    89 -VLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRD 152

  Fly   844 IKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENGPKPTVLERR 908
            :||:|:|:|...:||:.|||:..          .|.:.:
Yeast   153 LKPENLLLDSFYNIKIADFGMAA----------LQTDAD-------------------------- 181

  Fly   909 RMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLC-DYWSVGVILYEMLVGQPPF------LANSP 966
                    |..:..|:|:|.|||::....|.... |.||.||||:.:|.|:.||      :.:..
Yeast   182 --------LLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLL 238

  Fly   967 LETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGKSVDEVKSHDFFKGIDFADMRKQ 1031
            |:.|      :....:|...|:||:|.|||.::.. .|.|....:.::.||...|  .:..::..
Yeast   239 LKVQ------KGQFEMPNDTEISRDAQDLIGKILV-VDPRQRIKIRDILSHPLLK--KYQTIKDS 294

  Fly  1032 KAPYIPEIKH-PTDTSNFDPVDPEKLRSNDSTMSSGDD 1068
            |:     ||. |.:.:...|:    ..||:.|.:|.||
Yeast   295 KS-----IKDLPRENTYLYPL----ADSNNHTSASIDD 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	91/363 (25%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	79/312 (25%)
KCC4	NP_009907.2	PKc_like	19..285	CDD:419665	79/312 (25%)
KCC4	NP_009907.2	Kcc4p_like_C	920..1034	CDD:213379
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910