DRSC/TRiP Functional Genomics Resources

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Protein Alignment wts and CDC42BPA

DIOPT Version :9

Sequence 1:NP_733403.1 Gene:wts / 43651 FlyBaseID:FBgn0011739 Length:1105 Species:Drosophila melanogaster
Sequence 2:NP_001374479.1 Gene:CDC42BPA / 8476 HGNCID:1737 Length:1845 Species:Homo sapiens


Alignment Length:367 Identity:154/367 - (41%)
Similarity:222/367 - (60%) Gaps:59/367 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   708 RLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDIL 772
            ::|:.::.:..|..||.||.||||||.:| |:..::.::|||.|.|.::|||.:.|..:.|||:|
Human    66 KVKQMRLHREDFEILKVIGRGAFGEVAVV-KLKNADKVFAMKILNKWEMLKRAETACFREERDVL 129

  Fly   773 AEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFE----EELARFYIAEVTCAVDS 833
            ...||.|:..|:|:|||.:|||.||||..||||::||.|   ||    |::||||:||:..|:||
Human   130 VNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSK---FEDRLPEDMARFYLAEMVIAIDS 191

  Fly   834 VHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSEN 898
            ||::.::||||||||||:|.:|||:|.|||.|.                                
Human   192 VHQLHYVHRDIKPDNILMDMNGHIRLADFGSCL-------------------------------- 224

  Fly   899 GPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLE-----RSGYTQLCDYWSVGVILYEMLVGQ 958
                      ::.:...|.:...||||:||:||:|:     :..|...||:||:||.:||||.|:
Human   225 ----------KLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGE 279

  Fly   959 PPFLANSPLETQQKVINWEKTLHIPPQ-AELSREATDLIRRLCASADKRLGKS-VDEVKSHDFFK 1021
            .||.|.|.:||..|::|.::....|.| .::|..|.||||||..|.:.|||:: :::.|.|.||.
Human   280 TPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFS 344

  Fly  1022 GIDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTM 1063
            |||:.::|..:||||||:..|||||||| ||.:.|: |..||
Human   345 GIDWDNIRNCEAPYIPEVSSPTDTSNFD-VDDDCLK-NSETM 384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wtsNP_733403.1 STKc_LATS 717..1078 CDD:270749 153/358 (43%)
S_TKc 719..1020 CDD:214567 127/311 (41%)
CDC42BPANP_001374479.1 STKc_MRCK_alpha 4..412 CDD:270773 154/367 (42%)
SbcC 432..>941 CDD:223496
KELK 530..608 CDD:406277
C1_MRCKalpha 1062..1121 CDD:410414
PH_MRCK 1123..1257 CDD:269949
CNH 1283..1547 CDD:395630
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D759391at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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