DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wts and Cit

DIOPT Version :9

Sequence 1:NP_733403.1 Gene:wts / 43651 FlyBaseID:FBgn0011739 Length:1105 Species:Drosophila melanogaster
Sequence 2:XP_038945746.1 Gene:Cit / 83620 RGDID:70878 Length:2114 Species:Rattus norvegicus


Alignment Length:435 Identity:142/435 - (32%)
Similarity:217/435 - (49%) Gaps:101/435 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   659 QHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSMFVKLK 723
            :|:.:.::.|........:|:        |.....|:|.:                         
  Rat    71 KHVSSFVRKYSDTIAELRELQ--------PSVRDFEVRSL------------------------- 102

  Fly   724 PIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQ 788
             :|.|.|.||.:|.:..|.: :||||.::||.:..:.||:..:.||:||:::.:.|:.:|.|:||
  Rat   103 -VGCGHFAEVQVVREKATGD-VYAMKIMKKAALRAQEQVSFFEEERNILSQSTSPWIPQLQYAFQ 165

  Fly   789 DKDNLYFVMDYIPGGDLMSLLIKL-GIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILID 852
            ||:|||.||:|.|||||:|||.:. ...:|.:.:||:||:..||.|||:||::||||||:|||||
  Rat   166 DKNNLYLVMEYQPGGDLLSLLNRYEDQLDENMIQFYLAELILAVHSVHQMGYVHRDIKPENILID 230

  Fly   853 RDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENGPKPTVLERRRMRDHQRVL 917
            |.|||||.|||.....             |.::.|:..|                          
  Rat   231 RTGHIKLVDFGSAAKM-------------NSNKVDAKLP-------------------------- 256

  Fly   918 AHSLVGTPNYIAPEVL------ERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINW 976
                :|||:|:|||||      .|..|...||:|||||:.||||.|:.||...:...|...::|:
  Rat   257 ----IGTPDYMAPEVLTVMNEDRRGTYGLDCDWWSVGVVAYEMLYGKTPFTEGTSARTFNNIMNF 317

  Fly   977 EKTLHIPPQAELSREATDLIRRLCASADKRLGKSVDEVKSHDFFKGIDFADMRKQKAPYIPEIKH 1041
            ::.|..|...::|.|..|||:.|.....:||  ..:.:..|.||...|:.::|....|::|.:|.
  Rat   318 QRFLKFPDDPKVSSELLDLIQSLLCVQKERL--KFEGLCCHPFFARTDWNNIRNSPPPFVPTLKS 380

  Fly  1042 PTDTSNFDPVDPEK---LRSNDSTMS----SGDDVDQNDRTFHGF 1079
            ..||||||  :|||   :.|:...:|    ||:::     .|.||
  Rat   381 DDDTSNFD--EPEKNSWVSSSPCQLSPSGFSGEEL-----PFVGF 418

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wtsNP_733403.1 STKc_LATS 717..1078 CDD:270749 134/374 (36%)
S_TKc 719..1020 CDD:214567 113/307 (37%)
CitXP_038945746.1 STKc_CRIK 96..421 CDD:270752 138/402 (34%)
Smc 472..1363 CDD:224117
CRIK 1429..1484 CDD:410364
PH 1514..1633 CDD:395117
CNH 1678..1974 CDD:214481
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D759391at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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