DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wts and PDK1

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	NP_568138.1	Gene:	PDK1 / 830330	AraportID:	AT5G04510	Length:	491	Species:	Arabidopsis thaliana

Alignment Length:	409	Identity:	125/409 - (30%)
Similarity:	188/409 - (45%)	Gaps:	76/409 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   690 QTQIEMRKMLNQKESNYIRLKRAKMDKSMFVKL-------------KPIGVGAFGEVTLVSKIDT 741
            :.:.:.:.:|....||...:.|:   ||...|.             |..|||::.:|....|.:|
plant     5 EKEFDSKLVLQGNSSNGANVSRS---KSFSFKAPQENFTSHDFEFGKIYGVGSYSKVVRAKKKET 66

  Fly   742 SNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLM 806
            .. :||:|.:.|..:.|.|:.|:||.||.:|.:.::..::|||::|||..:||..::...||:|.
plant    67 GT-VYALKIMDKKFITKENKTAYVKLERIVLDQLEHPGIIKLYFTFQDTSSLYMALESCEGGELF 130

  Fly   807 SLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWT 871
            ..:.:.|...|:.||||.|||..|::.:|.||.|||||||:|:|:..|||||:.|||
plant   131 DQITRKGRLSEDEARFYTAEVVDALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFG-------- 187

  Fly   872 HNSKYYQENGNHSRQDSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERS 936
                            |::|.::     .:.|||......|.    |.:.|||..|:.||||..|
plant   188 ----------------SVKPMQD-----SQITVLPNAASDDK----ACTFVGTAAYVPPEVLNSS 227

  Fly   937 GYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCA 1001
            ..|...|.|::|..||:||.|..||...|.....|::|  .:.:..|  ...|..|.|||.||..
plant   228 PATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRII--ARDIKFP--NHFSEAARDLIDRLLD 288

  Fly  1002 SADKRLGKSVDE----VKSHDFFKGIDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDST 1062
            :...|...:..|    :|.|.||.|:|:.::|.|..|.:..          ||.........|.|
plant   289 TEPSRRPGAGSEGYVALKRHPFFNGVDWKNLRSQTPPKLAP----------DPASQTASPERDDT 343

  Fly  1063 MSS-------GDDV-DQND 1073
            ..|       ||.: .||:
plant   344 HGSPWNLTHIGDSLATQNE 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	120/382 (31%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	103/317 (32%)
PDK1	NP_568138.1	STKc_PDK1	42..311	CDD:270733	102/306 (33%)
PDK1	NP_568138.1	PH_3	388..490	CDD:405303
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910