Protein Alignment wts and Pdpk1

DIOPT Version :9

• Sequence 1: NP_733403.1
• Gene: wts / 43651
• FlyBaseID: FBgn0011739
• Length: 1105
• Species: Drosophila melanogaster
• Sequence 2: NP_112343.2
• Gene: Pdpk1 / 81745
• RGDID: 620307
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 143/561 - (25%)
• Similarity: 235/561 - (41%)
• Gaps: 165/561 - (29%)

  Fly   570 IQISNSNLATTPPIPP--AKYNNNSSNTGANSSGGSNGST--GTTASSSTSCKKI-KHASPIPER 629
            :.|.:|.:..:.|.|.  ......||:.|..|.....|||  ||||.:..|...: :|.:.:|.:
  Rat    12 VPIQSSVVLCSCPSPSMVRSQTEPSSSPGIPSGVSRQGSTMDGTTAEARPSTNPLQQHPAQLPPQ 76

  Fly   630 KKISKEKEEERKEFRIRQYSPQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIE 694
            .               |:..|:.|||.
  Rat    77 P---------------RKKRPEDFKFG-------------------------------------- 88

  Fly   695 MRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKR 759
                                        |.:|.|:|..|.|..::.||.. ||:|.|.|..::|.
  Rat    89 ----------------------------KILGEGSFSTVVLARELATSRE-YAIKILEKRHIIKE 124

  Fly   760 NQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYI 824
            |:|.:|..|||:::..|:.:.||||::|||.:.|||.:.|...|:|:..:.|:|.|:|...|||.
  Rat   125 NKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYT 189

  Fly   825 AEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSM 889
            ||:..|::.:|..|.||||:||:|||::.|.||::||||..                     ..:
  Rat   190 AEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTA---------------------KVL 233

  Fly   890 EPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEM 954
            .|                    |.::..|:|.|||..|::||:|......:..|.|::|.|:|::
  Rat   234 SP--------------------DSKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQL 278

  Fly   955 LVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCA-SADKRLG----KSVDEV 1014
            :.|.|||.|.:.....||:|..|...   |: :...:|.||:.:|.. .|.||||    :....:
  Rat   279 VAGLPPFRAGNEYLIFQKIIKLEYDF---PE-KFFPKARDLVEKLLVLDATKRLGCEEMEGYGPL 339

  Fly  1015 KSHDFFKGIDFADMRKQKAP----YIPEIKHPTDT--SNFDPVDPE----KLRSNDSTMS----- 1064
            |:|.||:.|.:.::.:|..|    |:|.:....:.  .|:|.:..:    ::.|:.|:.|
  Rat   340 KAHPFFESITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVD 404

  Fly  1065 ------SGDDVDQ--NDRTFHGF-----FEFTFRRFFDDKQ 1092
                  ||.:::|  :|...:.|     |....:|...:||
  Rat   405 ASLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQ 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	115/388 (30%)
		S_TKc	719..1020	CDD:214567	99/305 (32%)
Pdpk1	NP_112343.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..83		16/72 (22%)
		STKc_PDK1	83..345	CDD:270733	102/373 (27%)
		PIF-pocket. /evidence=ECO:0000250|UniProtKB:O15530	116..160		18/43 (42%)
		PH_PDK1	444..550	CDD:241293	2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910