DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wts and prkcd

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_002934267.1	Gene:	prkcd / 733756	XenbaseID:	XB-GENE-478663	Length:	683	Species:	Xenopus tropicalis

Alignment Length:	400	Identity:	137/400 - (34%)
Similarity:	216/400 - (54%)	Gaps:	60/400 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   687 LPDQTQIEMRKMLNQKESN-YIRL-KRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMK 749
            :||.|..:..::......: :|.| .|.|:|..:|.|:  :|.|:||:| |::::......:|:|
Frog   324 MPDATDNQYDRLWEGSSPHPHISLSSRLKIDNFVFHKV--LGKGSFGKV-LLAELKGKGEYFAIK 385

  Fly   750 TLRKADVLKRNQVAHVKAERDILAEA-DNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLG 813
            .|:|..||..:.|.....|:.:||.| :|.::..:|.|||.|::|:|||:::.|||||..:...|
Frog   386 ALKKDVVLIDDDVECTMVEKRVLALAWENPFLTHIYCSFQTKEHLFFVMEFLNGGDLMFHIQDKG 450

  Fly   814 IFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQ 878
            .|:...|.||.:|:.|.:..:|..|.|:||:|.||:::|:|||||:.|||:|            :
Frog   451 RFDLYRATFYASEIICGLQFLHSKGIIYRDLKLDNVMLDKDGHIKIADFGMC------------K 503

  Fly   879 ENGNHSRQDSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCD 943
            ||             .|.:|                  .|.:..|||:|||||:|:...||...|
Frog   504 EN-------------VYGDN------------------KASTFCGTPDYIAPEILQGLKYTFSVD 537

  Fly   944 YWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLC-ASADKRL 1007
            :||.||:|||||:||.||..:...|..:.:  .:.|.|.|  ..:::|:.|::.||. ....|||
Frog   538 WWSFGVLLYEMLIGQSPFHGDDEDELFESI--RQDTPHYP--RWITKESKDILERLFEREPTKRL 598

  Fly  1008 GKSVDEVKSHDFFKGIDFA--DMRKQKAPYIPEIKHPTDTSNFD-PVDPEKLRSNDSTMSSGDDV 1069
            | .|..:|.|.|||.|::.  :.|:.:.|:.|::|.|:|.|||| ....||.|.:.|..:..|.:
Frog   599 G-VVGNIKVHPFFKTINWTALERRELEPPFKPKVKSPSDYSNFDREFLSEKPRLSFSDKNLIDSM 662

  Fly  1070 DQNDRTFHGF 1079
            ||:  .||||
Frog   663 DQS--AFHGF 670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	126/365 (35%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	104/302 (34%)
prkcd	XP_002934267.1	C1_1	158..207	CDD:365894
		C1_1	230..280	CDD:365894
		STKc_nPKC_delta	360..675	CDD:173710	127/363 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910