DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and cdc42bpb

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_021324167.1	Gene:	cdc42bpb / 567039	ZFINID:	ZDB-GENE-030131-3647	Length:	1789	Species:	Danio rerio

Alignment Length:	363	Identity:	144/363 - (39%)
Similarity:	212/363 - (58%)	Gaps:	58/363 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   709 LKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILA 773
            :|..::.:..|..||.||.||||||.:| |:..:..:||||.|.|.::|||.:.|..:.||::|.
Zfish    66 VKEMRLHRDDFEMLKVIGRGAFGEVAVV-KMKHTERVYAMKILNKWEMLKRAETACFREERNVLV 129

  Fly   774 EADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFE----EELARFYIAEVTCAVDSV 834
            ..|..|:..|:|:|||.:.||.||||..||||::||.|   ||    |::|:||:||:..|:.|:
Zfish   130 NGDCQWITTLHYAFQDDNYLYLVMDYYVGGDLLTLLSK---FEDRLPEDMAKFYVAEMVLAIHSI 191

  Fly   835 HKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENG 899
            |:..::||||||||:|:|.:|||:|.|||.|.
Zfish   192 HQQRYVHRDIKPDNVLLDMNGHIRLADFGSCL--------------------------------- 223

  Fly   900 PKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLE-----RSGYTQLCDYWSVGVILYEMLVGQP 959
                     :|.....|.:...||||:||:||:|:     ...|...||:||:||.:||||.|:.
Zfish   224 ---------KMMQDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGET 279

  Fly   960 PFLANSPLETQQKVINWEKTLHIPPQ-AELSREATDLIRRLCASADKRLGK-SVDEVKSHDFFKG 1022
            ||.|.|.:||..|::|.|:....|.. .::|.:|.|||:||..|.::|||: .::|.:.|.||.|
Zfish   280 PFYAESLVETYGKIMNHEERFQFPSHITDVSEDAKDLIQRLICSRERRLGQHGIEEFRKHAFFSG 344

  Fly  1023 IDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSND 1060
            ||:.::|..:|||||::..|:|||||| ||.:.|::.|
Zfish   345 IDWENIRNMEAPYIPDVSSPSDTSNFD-VDDDVLKNPD 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	143/355 (40%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	121/311 (39%)
cdc42bpb	XP_021324167.1	PKc_like	3..411	CDD:328722	144/363 (40%)
		SbcC	<437..>935	CDD:223496
		KELK	524..602	CDD:318090
		C1	1039..1088	CDD:237996
		PH_MRCK	1098..1232	CDD:269949
		CNH	1258..1523	CDD:307087
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920