DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and cdc42bpab

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_021324156.1	Gene:	cdc42bpab / 566003	ZFINID:	ZDB-GENE-080219-17	Length:	1800	Species:	Danio rerio

Alignment Length:	401	Identity:	156/401 - (38%)
Similarity:	231/401 - (57%)	Gaps:	79/401 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   708 RLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDIL 772
            ::|:.::.|..|..||.||.||||||.:| |:..::.::|||.|.|.::|||.:.|..:.|||:|
Zfish    66 KVKQMRLHKEDFEILKVIGRGAFGEVAVV-KVKNTDKVFAMKILNKWEMLKRAETACFREERDVL 129

  Fly   773 AEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFE----EELARFYIAEVTCAVDS 833
            ...|..|:..|:|:|||::|||.||||..||||::||.|   ||    |::|:||:||:..|:||
Zfish   130 VNGDCQWITTLHYAFQDENNLYLVMDYYVGGDLLTLLSK---FEDRLPEDMAKFYLAEMVLAIDS 191

  Fly   834 VHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSEN 898
            ||::.::||||||||||:|.:|||:|.|||.|.
Zfish   192 VHQLHYVHRDIKPDNILMDMNGHIRLADFGSCL-------------------------------- 224

  Fly   899 GPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLE-----RSGYTQLCDYWSVGVILYEMLVGQ 958
                      ::.:...|.:...||||:||:||:|:     :..|...||:||:||.:||||.|:
Zfish   225 ----------KLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGKYGPECDWWSLGVCMYEMLYGE 279

  Fly   959 PPFLANSPLETQQKVINW-------EKTLHIPPQ-AELSREATDLIRRLCASADKRLGKS-VDEV 1014
            .||.|.|.:||..|::|.       |:....|.| .::|.:|.||:|||..|.:.|||:: :::.
Zfish   280 TPFYAESLVETYGKIMNHKSSQPNDEERFQFPLQVTDVSEDAKDLVRRLICSREHRLGQNGIEDF 344

  Fly  1015 KSHDFFKGIDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDS------TMSSGDDVDQND 1073
            |.|.||.|||:.::|..:||||||:..|||||||| ||.:.|::.::      |..||..:.
Zfish   345 KQHPFFTGIDWDNIRTCEAPYIPEVSSPTDTSNFD-VDDDCLKNCETLPPPSHTAFSGHHLP--- 405

  Fly  1074 RTFHGFFEFTF 1084
                 |..||:
Zfish   406 -----FVGFTY 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	151/384 (39%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	125/318 (39%)
cdc42bpab	XP_021324156.1	STKc_MRCK_alpha	4..419	CDD:270773	156/401 (39%)
		SbcC	438..>945	CDD:223496
		KELK	535..613	CDD:318090
		DMPK_coil	887..947	CDD:117396
		C1_1	1057..1107	CDD:278556
		PH_MRCK	1117..1251	CDD:269949
		CNH	1277..1539	CDD:307087
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920