DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wts and stk38l

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	NP_001006753.1	Gene:	stk38l / 448427	XenbaseID:	XB-GENE-5881027	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	497	Identity:	211/497 - (42%)
Similarity:	301/497 - (60%)	Gaps:	73/497 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   610 TASSSTSCKKIKHASPIPERKKISKEKEEERKEFRIRQYSPQAFKFFMEQHIENVIKSYRQRTYR 674
            ||::.|||....|.     |::::                  ..|..:|....|:|..:.:|..|
Frog     4 TATNPTSCPMSSHT-----RERVT------------------VAKLTLETFYSNLILQHEERETR 45

  Fly   675 KNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKI 739
            :.:||..|.:.||.|..:...|....:||:.::||||.::....|..||.||.||||||.||.|.
Frog    46 QKKLEVAMEEEGLGDDEKKMRRSQHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKK 110

  Fly   740 DTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGD 804
            || .|:||||.|||||:|::.||||::||||||.|||..||||::||||||.|||.:|:::||||
Frog   111 DT-GHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGD 174

  Fly   805 LMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFR 869
            :|:||:|.....||..:|||||...|:|::|::|||||||||||:|:|..||:||:|||||||.:
Frog   175 MMTLLMKKDTLTEEATQFYIAETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLK 239

  Fly   870 WTHNSKYYQ------------ENGNHSRQDSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLV 922
            ..|.:::|:            :|.|..|:  .|.|::                  ::|.||:|.|
Frog   240 KAHRTEFYRNLTHNPPSDFSFQNMNSKRK--AETWKK------------------NRRQLAYSTV 284

  Fly   923 GTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAE 987
            |||:||||||..::||.:|||:||:|||:||||:|.|||.:.:|.||.:||:||::||..||:..
Frog   285 GTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVP 349

  Fly   988 LSREATDLIRRLCASADKRLGKS-VDEVKSHDFFKGIDFADMRKQKAPYIPEIKHPTDTSNFDPV 1051
            .|.::.|||.|.||.::.|:|.: |:|:|||.||:|:|:..:|::.|....|||...||||||..
Frog   350 TSEKSKDLILRFCADSENRVGSNGVEEIKSHPFFEGVDWGHIRERPAAIPIEIKSIDDTSNFDEF 414

  Fly  1052 DPEK------LRSNDSTMSSGDDVDQNDRTFHGFFEFTFRRF 1087
             ||.      |...:....|.|.|         |..:|::||
Frog   415 -PESDILQPVLNPPEPDYKSKDWV---------FLNYTYKRF 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	181/379 (48%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	160/313 (51%)
stk38l	NP_001006753.1	STKc_NDR2	87..452	CDD:270776	185/391 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216969at33208
OrthoFinder	1	1.000	-	-		FOG0000273
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010