Protein Alignment wts and dop

DIOPT Version :9

• Sequence 1: NP_733403.1
• Gene: wts / 43651
• FlyBaseID: FBgn0011739
• Length: 1105
• Species: Drosophila melanogaster
• Sequence 2: NP_001261884.1
• Gene: dop / 39686
• FlyBaseID: FBgn0267390
• Length: 2139
• Species: Drosophila melanogaster
• Alignment Length: 1256
• Identity: 304/1256 - (24%)
• Similarity: 454/1256 - (36%)
• Gaps: 430/1256 - (34%)

  Fly    16 YTAEALESIKQDLTRFEVQNNHRNN--------QNYTPLRYTATNGRNDALTPDYHH----AKQP 68
            |||         |.|......|.|:        .|...:|:::.......||.:|..    |..|
  Fly   200 YTA---------LLRKISYQQHTNSLRAVSGETSNLLRMRHSSLGKSAPCLTGNYFRHELTAPLP 255

  Fly    69 MEPPP-SASPAPDVVIPPPPAIVGQPGAGSISVSG--VGVGVVGVANGRVPKMMTALMPNKLIRK 130
            ::||. .|||.               |..:||.||  .|:|:
  Fly   256 VQPPGFGASPL---------------GGHNISRSGSCAGIGL----------------------- 282

  Fly   131 PSIERDTASSHYLRCSPALDSGAGSSRSDSPHSHHTHQPSSR-TVGNPGGNGGFSPSPSGFSEVA 194
                    :.|:                   |.||.|....| :.|...|:||.|.|......::
  Fly   283 --------AKHH-------------------HHHHLHGVVMRGSAGGGAGSGGGSSSGVAHHRLS 320

  Fly   195 PPAPPPRNPTACSAATPPPPVPPTSQAYVKRRSPALNNRPPAIAPPTQR---------------- 243
            ...    |..|.:||.......|.|.:.|.  ||.||:..|....|.:|
  Fly   321 LVT----NSAAVAAAGGSRTHSPYSASPVD--SPRLNSPMPFAFAPIKRIASCRGVVADGRRWSV 379

  Fly   244 --------GNSPVITQNGLKNPQQQLTQQ--LKSL--NLYPGGGSGAVVEPPPPYLIQGGAGGA- 295
                    |.:|     |..|...|.:.|  |..|  |:.||      |:......:..||..|
  Fly   380 ASLPSSGYGTTP-----GSSNLSSQCSSQEGLNQLAHNIPPG------VQEADAAAVAAGACCAE 433

  Fly   296 ---------------------APPPPPPSYTASMQSRQSPTQS--------------QQSDYRKS 325
                                 .|.||.|:   .:|.::|.|.:              ||:.  ..
  Fly   434 HLKQHCPKHCALLLAVSQKQLTPQPPKPT---QLQPQKSMTAACVNCCAELSVTCGGQQAG--GG 493

  Fly   326 PSSGIYSATSAGSPSPITVSLPPAPLAKPQPRVYQARSQQPIIMQSV------------KSTQVQ 378
            .::|..||.|:|| |.:.|....:|..:|:.|...:.|:.||:...:            |:||..
  Fly   494 AANGGSSANSSGS-SAMQVGGRMSPYFRPRSRSLSSPSRSPIVDNEIAVMNTLYKERFPKATQQM 557

  Fly   379 KPVLQTAVAPQSPSSASASNS-----PV------HVLAAPPSYPQKSAAVVQQQQQAAAAAHQQQ 432
            :..|:..:   :.:.::|.||     |:      .||........||.|.:...|.....:...:
  Fly   558 EERLKLFI---NENKSAACNSFRDSQPIVRFVHHQVLEMARDCLHKSEAKLITSQYFYELSENLE 619

  Fly   433 HQHQQSKPPTP--------TTPPLVGLNSKP----NCLE--PPSYAKSMQ-----AKAATVVQQQ 478
            ....::|..:|        ....|:.:.|:|    .|||  |..:.:.::     |||..|::..
  Fly   620 RLLVETKEKSPEAAAELNGVIKKLLLIISRPARLLECLEFDPQEFYELLEAAEGHAKAMPVIKAD 684

  Fly   479 QQQ--------QQQQQQVQQQQVQQQQQQQQQQLQALRVLQAQAQRERDQRERDQRERERDQQKL 535
            ..|        .:......||::::.||...:|:..                        |...|
  Fly   685 IPQYIIHKLGLNRDPIAELQQELRETQQMCSEQVTV------------------------DADPL 725

  Fly   536 ANGNPGRQMLPPPPYQSNNNNNSEIKPPSCNNNNIQISNSNLATTPPIPP--------------- 585
               :||..:|...|..|.....|.:...:     |.:.:.:...||..||
  Fly   726 ---HPGGSLLLNSPLTSAAKQLSSLALDA-----IAMDSGSGTATPQQPPQTPVATCDTAPSFAL 782

  Fly   586 ------AKYNNNSSNTGANSS---GGSNGSTGTTASSSTSCKKIKHASPIPERKKISKEKEEERK 641
                  .:...:||..|..||   .|:.|.||.:|:::|..
  Fly   783 AISQMNEEKGGSSSAVGGGSSSKVAGAEGITGGSAATATGS------------------------ 823

  Fly   642 EFRIRQYSPQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNY 706
              ..:|.|||...|.:.:.|.|
  Fly   824 --GAQQPSPQENDFDIVKLISN------------------------------------------- 843

  Fly   707 IRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDI 771
                                 ||:|.|.|| |..|:...:|||.:.|.:::.||||..|.|||||
  Fly   844 ---------------------GAYGAVYLV-KHKTTRQRFAMKKINKNNLILRNQVEQVFAERDI 886

  Fly   772 LAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHK 836
            |:.|||.:||.:|.||:.|.:|..||:|:.|||..:||..:|....::||||.||...||:.:|.
  Fly   887 LSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHS 951

  Fly   837 MGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENGPK 901
            .|.:|||:||||:||...||||||||||             .:.|..|...::  :|.|.::
  Fly   952 YGIVHRDLKPDNLLITALGHIKLTDFGL-------------SKMGLMSLATNL--YEGYIDS--- 998

  Fly   902 PTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSP 966
                |.|:..|.|      :.|||.||||||:.|.||.:..|:||:|:||||.|:|..||...:.
  Fly   999 ----ETRQFSDKQ------VYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETT 1053

  Fly   967 LE----TQQKVINWEKTLHIPPQAELSREATDLIRRLCASADK-RLG--KSVDEVKSHDFFKGID 1024
            .|    |....|.|..:...|.||    ||.|:|.:|.....: |||  ....|:|.|::|.|:|
  Fly  1054 EELFAHTVNDDIEWPDSEDWPVQA----EAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMD 1114

  Fly  1025 FADMRKQKAPYIPEIKHPTDTSNFDP-VDPEKLRSNDSTMSSGDDVDQNDRT--FHGFFEFT--F 1084
            :..:.:|||.::|::.|..|||.||. :|    |.|...  .|:|.|..|.|  |..|..:|  :
  Fly  1115 WNSLLRQKAEFVPQLSHDDDTSYFDTRMD----RYNHDL--GGEDTDDTDDTPVFGSFNSYTPQY 1173

  Fly  1085 RR---FFDDKQPPDMTDDQAP 1102
            |:   .:.....|..||...|
  Fly  1174 RKQHYSWSRHATPTSTDGAKP 1194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	143/370 (39%)
		S_TKc	719..1020	CDD:214567	121/307 (39%)
dop	NP_001261884.1	DUF1908	344..702	CDD:286070	74/379 (20%)
		STKc_MAST	834..1115	CDD:270760	126/377 (33%)
		S_TKc	835..1110	CDD:214567	124/371 (33%)
		PDZ_signaling	1506..1587	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458917
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940