DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wts and gek

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	NP_523837.2	Gene:	gek / 37858	FlyBaseID:	FBgn0023081	Length:	1637	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	151/404 - (37%)
Similarity:	222/404 - (54%)	Gaps:	73/404 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   704 SNYIRL--------KRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRN 760
            |::::|        ::.::.:..|..||.||.||||||.:|..|.|.. :||||.|.|.::|||.
  Fly    77 SDFLKLSKPFVHIVRKLRLSRDDFDILKIIGRGAFGEVCVVQMISTEK-VYAMKILNKWEMLKRA 140

  Fly   761 QVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFE----EELAR 821
            :.|..:.|||:|...|..|:..|:|:|||..|||.||||..||||::||.|   ||    |::|:
  Fly   141 ETACFREERDVLVFGDRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSK---FEDKLPEDMAK 202

  Fly   822 FYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQ 886
            |||.|:..|::|:|::.::||||||||:|:|:.||::|.|||.|.
  Fly   203 FYITEMILAINSIHQIRYVHRDIKPDNVLLDKRGHVRLADFGSCL-------------------- 247

  Fly   887 DSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLE-----RSGYTQLCDYWS 946
                                  |:.....|.::..||||:||:||:|.     :..|...||:||
  Fly   248 ----------------------RLDKDGTVQSNVAVGTPDYISPEILRAMEDGKGRYGTECDWWS 290

  Fly   947 VGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAEL----SREATDLIRRLCASADKRL 1007
            :||.:||||.|:.||.|.|.:||..|::|.:...::|.|..|    |..:.||:.:|....:.||
  Fly   291 LGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLICIPENRL 355

  Fly  1008 GKS-VDEVKSHDFFKGIDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGDDVDQ 1071
            |:: :.:...|.:|.|||:.::|:..|||:||:..|||||||| ||...:|..||...|.:....
  Fly   356 GQNGIQDFMDHPWFVGIDWKNIRQGPAPYVPEVSSPTDTSNFD-VDDNDVRLTDSIPPSANPAFS 419

  Fly  1072 NDRTFH-GFFEFTF 1084
            .   || .|..|||
  Fly   420 G---FHLPFIGFTF 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	145/375 (39%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	119/314 (38%)
gek	NP_523837.2	STKc_DMPK_like	98..430	CDD:270748	147/381 (39%)
		S_TKc	100..369	CDD:214567	119/314 (38%)
		KELK	478..556	CDD:292424
		CEP63	492..749	CDD:293650
		CEP63	652..880	CDD:293650
		C1_1	990..1040	CDD:278556
		PH_MRCK	1049..1182	CDD:269949
		CNH	1211..1486	CDD:279162
		CRIB	1544..1580	CDD:238077
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D21674at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920