DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and Dmpk

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_038967160.1	Gene:	Dmpk / 308405	RGDID:	1309825	Length:	646	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	146/370 - (39%)
Similarity:	213/370 - (57%)	Gaps:	60/370 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   708 RLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDIL 772
            |||..::.:..|..||.||.|||.||.:| |:..:..:||||.:.|.|:|||.:|:..:.|||:|
  Rat    60 RLKEVRLQRDDFEILKVIGRGAFSEVAVV-KMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVL 123

  Fly   773 AEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLG-IFEEELARFYIAEVTCAVDSVHK 836
            .:.|..|:.:|:::|||::.||.||:|..||||::||.|.| ....|:||||:||:..|:||||:
  Rat   124 VKGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHR 188

  Fly   837 MGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENGPK 901
            :|::||||||||||:||.|||:|.|||.|...:                              |.
  Rat   189 LGYVHRDIKPDNILLDRCGHIRLADFGSCLKLQ------------------------------PD 223

  Fly   902 PTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSG-------YTQLCDYWSVGVILYEMLVGQP 959
            .||          |.|.  .||||:|::||:|:..|       |...||:|::||..|||..||.
  Rat   224 GTV----------RSLV--AVGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYEMFYGQT 276

  Fly   960 PFLANSPLETQQKVINWEKTLHIPPQAELS--REATDLIRRLCASADKRLGK-SVDEVKSHDFFK 1021
            ||.|:|..||..|::::.:.|.: |:|::.  .||.||||.|...|:.|||: ...:.:.|.||.
  Rat   277 PFYADSTAETYAKIVHYREHLSL-PRADMGVPEEAQDLIRGLLCPAEIRLGRGGAGDFQKHPFFF 340

  Fly  1022 GIDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSG 1066
            |:|:..:|....|:.|:.:..|||.|||.|: ::|    :.|.||
  Rat   341 GLDWEGLRDSVPPFTPDFEGATDTCNFDVVE-DRL----TAMVSG 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	143/361 (40%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	125/311 (40%)
Dmpk	XP_038967160.1	PKc_like	69..406	CDD:419665	143/361 (40%)
Dmpk	XP_038967160.1	DMPK_coil	472..532	CDD:117396
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920