DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and Rock2

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_008762796.1	Gene:	Rock2 / 25537	RGDID:	3590	Length:	1473	Species:	Rattus norvegicus

Alignment Length:	411	Identity:	149/411 - (36%)
Similarity:	220/411 - (53%)	Gaps:	71/411 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   699 LNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVA 763
            ||:.|....:::..:|....:..:|.||.||||||.|| :...|..:||||.|.|.:::||:..|
  Rat    72 LNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLV-RHKASQKVYAMKLLSKFEMIKRSDSA 135

  Fly   764 HVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVT 828
            ....||||:|.|::.|||:|:.:|||...||.||:|:|||||::|:....: .|:.|:||.|||.
  Rat   136 FFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVV 199

  Fly   829 CAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWE 893
            .|:|::|.||.||||:||||:|:|:.||:||.|||.|
  Rat   200 LALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTC---------------------------- 236

  Fly   894 EYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSG----YTQLCDYWSVGVILYEM 954
                          .:|.:...|...:.||||:||:||||:..|    |.:.||:|||||.|:||
  Rat   237 --------------MKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEM 287

  Fly   955 LVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGKS-VDEVKSHD 1018
            |||..||.|:|.:.|..|:::.:.:|..|...|:|:.|.:||.......:.|||:: |:|:|.|.
  Rat   288 LVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRNGVEEIKQHP 352

  Fly  1019 FFKG--IDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGDDVDQ---------N 1072
            |||.  .::.::|:..||.:||:....|:||||.::.:|           .||:.         |
  Rat   353 FFKNDQWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDK-----------GDVETFPIPKAFVGN 406

  Fly  1073 DRTFHGFFEFTFRRFFDDKQP 1093
            ...|.||..|.......|..|
  Rat   407 QLPFIGFTYFRENLLLSDSPP 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	140/376 (37%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	122/305 (40%)
Rock2	XP_008762796.1	STKc_ROCK2	39..417	CDD:270771	146/399 (37%)
		S_TKc	92..354	CDD:214567	122/305 (40%)
		Smc	<437..1101	CDD:224117
		HR1_ROCK2	505..571	CDD:212028
		Rho_Binding	979..1046	CDD:286056
		PH_ROCK	1208..1314	CDD:269948
		C1	1318..1364	CDD:237996
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920