DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and Stk38l

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_006507092.1	Gene:	Stk38l / 232533	MGIID:	1922250	Length:	477	Species:	Mus musculus

Alignment Length:	459	Identity:	196/459 - (42%)
Similarity:	286/459 - (62%)	Gaps:	55/459 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   654 KFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSM 718
            |..:|....|:|..:.:|..|:.:||..|.:.||.|:.:...|....:||:.::||||.::....
Mouse    31 KLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDD 95

  Fly   719 FVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKL 783
            |..||.||.||||||.||.|.|| .|:||||.|||||:|::.||||::||||||.|||..||||:
Mouse    96 FESLKVIGRGAFGEVRLVQKKDT-GHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKM 159

  Fly   784 YYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDN 848
            :||||||.|||.:|:::||||:|:||:|.....||..:|||:|...|:|::|::||||||:||||
Mouse   160 FYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGFIHRDVKPDN 224

  Fly   849 ILIDRDGHIKLTDFGLCTGFRWTHNSKYYQ------------ENGNHSRQDSMEPWEEYSENGPK 901
            :|:|..||:||:|||||||.:..|.:::|:            :|.|..|:  .|.|::
Mouse   225 LLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRK--AETWKK------- 280

  Fly   902 PTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSP 966
                       ::|.||:|.||||:||||||..::||.:|||:||:|||:||||:|.|||.:.:|
Mouse   281 -----------NRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGFPPFCSETP 334

  Fly   967 LETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGK-SVDEVKSHDFFKGIDFADMRK 1030
            .||.:||::|::||..||:..:|.:|.|||.|.|..::.|:|. .|:|:|.|.||:|:|:..:|:
Mouse   335 QETYRKVMSWKETLAFPPEVPVSEKAKDLILRFCTDSENRIGNGGVEEIKGHPFFEGVDWGHIRE 399

  Fly  1031 QKAPYIPEIKHPTDTSNFDPVDPEKL------------RSNDSTMSSGDDVDQNDRTFHGFFEFT 1083
            :.|....||:...||||||......:            .:.:....|.|.|         |..:|
Mouse   400 RPAAIPIEIRSIDDTSNFDDFPESDILQPVAFFLFLVPNTTEPDYKSKDWV---------FLNYT 455

  Fly  1084 FRRF 1087
            ::||
Mouse   456 YKRF 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	173/385 (45%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	156/313 (50%)
Stk38l	XP_006507092.1	STKc_NDR2	93..465	CDD:270776	177/397 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216969at33208
OrthoFinder	1	1.000	-	-		FOG0000273
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920