DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wts and sax-1

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	NP_508627.5	Gene:	sax-1 / 180655	WormBaseID:	WBGene00004727	Length:	476	Species:	Caenorhabditis elegans

Alignment Length:	452	Identity:	203/452 - (44%)
Similarity:	287/452 - (63%)	Gaps:	19/452 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   642 EFRIRQYS---PQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKE 703
            |..|.||:   ....:..:|.:....:....:|..|..:||:::...||.|:.:.|.||:.:.||
Worm     7 EMEISQYTKDKASCTRISIESYYSKRVTQCAERENRLKKLEEDISARGLSDEEKEEKRKIHHSKE 71

  Fly   704 SNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAE 768
            ::|:||||.::..:.|..||.||.||||||.||.|.|| .|:||||.|||::::::.|.|||:||
Worm    72 TDYLRLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDT-GHIYAMKILRKSEMVEKEQTAHVRAE 135

  Fly   769 RDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDS 833
            ||||:|||.:||||:||||||..|||.||:::||||:|:||||.....||..:|||||...|:..
Worm   136 RDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQFYIAEAALAIQF 200

  Fly   834 VHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSM-EPWEEYSE 897
            :|.:|||||||||||:|:|..||:||:|||||||.:..|.:.:|:...:....|.: :|:    |
Worm   201 IHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNWPSTLPPDFISKPF----E 261

  Fly   898 NGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFL 962
            :..|....:|.|     |..|:|.||||:||||||.:.:|||:.||:||:|||:||||:|.|||.
Worm   262 SKRKAETWKRNR-----RAYAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGVIMYEMLIGYPPFC 321

  Fly   963 ANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGK--SVDEVKSHDFFKGIDF 1025
            :..|.||.:|||||::||..|....:|.||...|:|.|..|::|||.  .:||:|...|.|.||:
Worm   322 SELPQETYRKVINWQQTLVFPSDVPISIEAKATIKRFCCEAERRLGNHGGLDEIKQCPFVKRIDW 386

  Fly  1026 ADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGDDVDQNDRTFHGFFEFTFRRF 1087
            ..:|::..|....:|...||||||....|.|....||:...:  :|..|... |.:||::||
Worm   387 NHIRERPPPIRVTVKSIDDTSNFDDFPDEDLTWPTSTLIRPE--EQPGRRGE-FVDFTYKRF 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	176/363 (48%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	157/303 (52%)
sax-1	NP_508627.5	STKc_NDR_like	85..443	CDD:270750	179/370 (48%)
sax-1	NP_508627.5	S_TKc	87..381	CDD:214567	157/303 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216969at33208
OrthoFinder	1	1.000	-	-		FOG0000273
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920