DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wts and pdk-1

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	NP_001024743.1	Gene:	pdk-1 / 180475	WormBaseID:	WBGene00003965	Length:	636	Species:	Caenorhabditis elegans

Alignment Length:	356	Identity:	102/356 - (28%)
Similarity:	174/356 - (48%)	Gaps:	28/356 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   710 KRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAE 774
            ||...|   |:.|:.:|.||:.:|....::.| :.::|:|.|:|:.:.:..::..:..|::||..
Worm    63 KRTSND---FMFLQSMGEGAYSQVFRCREVAT-DAMFAVKVLQKSYLNRHQKMDAIIREKNILTY 123

  Fly   775 ADNN-----WVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSV 834
            ....     :|.:||..|.|:..:|||:..:..|||...|...|.|:...::|:.:|:...:..:
Worm   124 LSQECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQFL 188

  Fly   835 HKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENG 899
            |....:|||:||||:||.:||||.:||||....|.....|   ||....:.|.|    ...|::|
Worm   189 HDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLS---QEGFTDANQAS----SRSSDSG 246

  Fly   900 -PKPT-VLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFL 962
             |.|| ......:.:.......:.|||..|::||:|.........|.|.:|.||::.|.|||||.
Worm   247 SPPPTRFYSDEEVPEENTARRTTFVGTALYVSPEMLADGDVGPQTDIWGLGCILFQCLAGQPPFR 311

  Fly   963 ANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGKSVDEVKSHDFFKGIDFAD 1027
            |.:.....:::...:.:.   |:. ...||:::|.::.. .|.....:..|:.:|.||:.:|:.:
Worm   312 AVNQYHLLKRIQELDFSF---PEG-FPEEASEIIAKILV-RDPSTRITSQELMAHKFFENVDWVN 371

  Fly  1028 MRKQKAP----YIP-EIKHPTDTSNFDPVDP 1053
            :...|.|    ||| ....|...||..||:|
Worm   372 IANIKPPVLHAYIPATFGEPEYYSNIGPVEP 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	99/349 (28%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	85/307 (28%)
pdk-1	NP_001024743.1	STKc_PDK1	67..364	CDD:270733	86/312 (28%)
		S_TKc	69..364	CDD:214567	85/307 (28%)
		PH_PDK1	464..570	CDD:241293
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910