Protein Alignment wts and wts-1

DIOPT Version :9

• Sequence 1: NP_733403.1
• Gene: wts / 43651
• FlyBaseID: FBgn0011739
• Length: 1105
• Species: Drosophila melanogaster
• Sequence 2: NP_492699.1
• Gene: wts-1 / 172896
• WormBaseID: WBGene00007047
• Length: 908
• Species: Caenorhabditis elegans
• Alignment Length: 994
• Identity: 327/994 - (32%)
• Similarity: 470/994 - (47%)
• Gaps: 227/994 - (22%)

  Fly   134 ERDTASSHYLRCSPALDSGAGSSRSDSPHSHHTHQPSSRTVGNPGGNGGFSPSPSGFSEVAPPAP 198
            |....|||.     ||.|.|..|.|...||..|:  .:..|.|      ||.|.|..:..
 Worm    65 EAGLLSSHV-----ALGSLATPSSSSVSHSDITN--DNAEVMN------FSSSSSNAAAT----- 111

  Fly   199 PPRNPTACSAATPPPPVPPTSQAYVKRRSPALNNRPPAIAPPTQR------GNSPVITQNGLK-- 255
               ..|..|||........|.....|.|          |.|..||      |.:..:.::|.:
 Worm   112 ---TTTVSSAAVSNSNSFRTEGGGHKMR----------ITPMPQRHLMMDTGANETVFRSGKEMI 163

  Fly   256 ---NPQQQL-----TQQLKSLNLYPGGGSGAVVEPPPPYLIQGGAGGAAP---PPPPPSYTAS-M 308
               ||...:     |...:|:.::|.|....:  |.|.|.:...|...:|   .||||:|.:| :
 Worm   164 RNGNPSTTISSTPSTTTEESIRIHPAGYRYDM--PTPAYHMNNNAPQYSPGYSRPPPPAYDSSPV 226

  Fly   309 QSRQSPTQSQQSDYRKSPSSGIYSATSAGSPSPITVSLPPAPLAKPQPRVYQARSQQPIIMQSVK 373
            .:|.:|..:  .:||......::         |:..:.||                .|.::...|
 Worm   227 NTRMTPVAT--DNYRTHLHMKVH---------PVVKAPPP----------------NPTMLNHNK 264

  Fly   374 STQVQKPVLQTAVAPQSPSSASASNSPVHVLAAPPSYPQKSAAVVQQQQQAAAAAHQQQHQHQQS 438
            :                             :|.||..|.||...::...:...|.:.|:..|...
 Worm   265 N-----------------------------MAPPPPPPAKSTISIETMSEERKADNIQRLYHTSM 300

  Fly   439 KPPTPTTPPLVGLN------SKPNCLEPPSYAKSMQAKAATVVQQQQQQQQQQQQVQQQQVQQQQ 497
            ...|.::  :|.:|      :|.|..:.|..:||.      ::..:
 Worm   301 DKKTASS--VVSINVASPHTTKVNVGDSPLPSKSF------IIGPR------------------- 338

  Fly   498 QQQQQQLQALRVLQAQAQRERDQRERDQRERERDQQKLANGNPGRQMLPPPPYQSNNNNNSEIKP 562
                        ..|...|:.....:|:.            .|..:::|    .:::.|:.:.:|
 Worm   339 ------------YTADVDRKNFVNYKDEL------------RPDPRLIP----STSDANHEDFRP 375

  Fly   563 PSCNNNNIQISNSNLATTPPIPPAKYNNNSSNTGANSSGGSNGSTGTTASSSTSCKKIKHASPIP 627
            ......|::|:..:.|..   ||.:||.                     .|....|::  :|||
 Worm   376 ILFKPRNLEITMKSRAQP---PPPQYNQ---------------------PSEPPPKRV--SSPI- 413

  Fly   628 ERKKISKEKEEERKEFRIRQYSPQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQ 692
            :|..:....:..|   |::...|...:|:||||:|.:::.|::|..|..||||||....|||..:
 Worm   414 DRTLLEPYIKNTR---RVQPCKPNMLRFYMEQHVERLLQQYKEREKRMKQLEKEMVSAQLPDIMR 475

  Fly   693 IEMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVL 757
            .:|..:|.||||.|.||:|.||.||.|..:..|||||||:|:||.|.|| ..:||||:|.||||:
 Worm   476 NKMLGLLQQKESKYTRLRRQKMSKSHFTVISHIGVGAFGKVSLVRKNDT-RKVYAMKSLEKADVI 539

  Fly   758 KRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARF 822
            .:.|.||||||||||||||:.|:|:|::||||...|||:|:|:||||:|:|||:.|||||:||||
 Worm   540 MKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDLARF 604

  Fly   823 YIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQD 887
            ||||:.||::.||.:||||||:||||||||:.|||||||||||||.||||:.:||....:|.|.|
 Worm   605 YIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVD 669

  Fly   888 SMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILY 952
            |.....|.:.......||..|:..  :|:.|||||||.||:||||:.::|:.|.||:||.|||||
 Worm   670 SFSLPPEVAAIDKSVKVLNVRQQT--RRITAHSLVGTGNYMAPEVIAKTGHNQSCDWWSTGVILY 732

  Fly   953 EMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRL---GKSVDE- 1013
            ||:.|:.||..::|..||.::.||...|.......||:|...:|::|...|..||   ||.|.|
 Worm   733 EMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQQLICDASSRLGSHGKDVAER 797

  Fly  1014 ---VKSHDFFKGIDFADMRKQKAP--YIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGDDVDQ-N 1072
               ||:|.:|:|||:.::||.:|.  |||.:.|..|||||:            |....|..|: |
 Worm   798 TAQVKNHPWFRGIDWVNLRKLRADYIYIPRVTHDEDTSNFE------------TFQDNDRADKPN 850

  Fly  1073 DRTFH--GFFEFTFRRFFD 1089
            .|..|  .|:|||:|.|||
 Worm   851 VRGLHNPAFYEFTYRHFFD 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	190/372 (51%)
		S_TKc	719..1020	CDD:214567	167/307 (54%)
wts-1	NP_492699.1	STKc_LATS	500..868	CDD:270749	195/382 (51%)
		S_TKc	502..807	CDD:214567	167/307 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163331
Domainoid	1	1.000	326	1.000	Domainoid score	I639
eggNOG	1	0.900	-	-		E1_KOG0608
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	442	1.000	Inparanoid score	I928
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216969at33208
OrthoFinder	1	1.000	-	-		FOG0000273
OrthoInspector	1	1.000	-	-		oto19847
orthoMCL	1	0.900	-	-		OOG6_105652
Panther	1	1.100	-	-	LDO	PTHR24356
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2473
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.760