DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and AgaP_AGAP012090

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_320436.4	Gene:	AgaP_AGAP012090 / 1280583	VectorBaseID:	AGAP012090	Length:	1642	Species:	Anopheles gambiae

Alignment Length:	411	Identity:	146/411 - (35%)
Similarity:	211/411 - (51%)	Gaps:	99/411 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   693 IEMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVL 757
            ||:.|.:.|.      :|:.::.:..|..||.||.||||||.:|....|| .:||||.|.|.::|
Mosquito    30 IELMKSVVQS------VKQLRLSRDDFEVLKVIGRGAFGEVCVVRMHHTS-QIYAMKILNKWEML 87

  Fly   758 KRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFE----EE 818
            ||.:.|..:.|||:|...|..|:..|:|:|||..|||.:|||..||||::||.|   ||    |:
Mosquito    88 KRAETACFREERDVLVFGDRRWITNLHYAFQDDINLYLIMDYYCGGDLLTLLSK---FEDRLPED 149

  Fly   819 LARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNH 883
            :|||||||:..|:                       ||::|.|||.|...
Mosquito   150 MARFYIAEMVLAI-----------------------GHVRLADFGSCLRL--------------- 176

  Fly   884 SRQDSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLE-----RSGYTQLCD 943
                           ||:.|            |.::..||||:||:||:|.     :..|...||
Mosquito   177 ---------------GPQGT------------VQSNVAVGTPDYISPEILRAMEDGQGKYGPECD 214

  Fly   944 YWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAE---LSREATDLIRRLCASADK 1005
            :||:||.:||||.|:.||.|.|.:||..|::|.:.:...|...:   :|.:|.||||||..:.:.
Mosquito   215 WWSLGVCMYEMLFGETPFYAESLVETYGKIMNHKNSFDFPNDDDEFGVSEQAKDLIRRLICAPEY 279

  Fly  1006 RLGKS-VDEVKSHDFFKGIDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGDDV 1069
            |||:: :|:.|:|.:|:||.:..:|..:||||||:..|||||||| ||...::.:|:...:
Mosquito   280 RLGQNGIDDFKAHPWFEGISWDTIRNGQAPYIPEVSSPTDTSNFD-VDDTDIKLSDAVPPT---- 339

  Fly  1070 DQNDRTFHG----FFEFTFRR 1086
              .:..|.|    |..|||.:
Mosquito   340 --TNPAFSGHHLPFVGFTFTK 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	136/373 (36%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	114/313 (36%)
AgaP_AGAP012090	XP_320436.4	STKc_DMPK_like	48..357	CDD:270748	140/384 (36%)
		S_TKc	50..295	CDD:214567	114/313 (36%)
		Ax_dynein_light	<385..475	CDD:287215
		KELK	434..512	CDD:292424
		COG1340	457..758	CDD:224259
		DUF4200	473..>566	CDD:290574
		DMPK_coil	757..816	CDD:117396
		C1_1	941..991	CDD:278556
		PH_MRCK	1000..1133	CDD:269949
		PH	1013..1128	CDD:278594
		CNH	1162..1435	CDD:279162
		CRIB	1494..1532	CDD:238077
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D21674at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920