DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and AgaP_AGAP006932

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_308829.4	Gene:	AgaP_AGAP006932 / 1270154	VectorBaseID:	AGAP006932	Length:	1908	Species:	Anopheles gambiae

Alignment Length:	505	Identity:	156/505 - (30%)
Similarity:	228/505 - (45%)	Gaps:	133/505 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   601 GGSNGSTGTTASSSTSCKKIKHASPIPERK----------KISKEKEEERKEFRIRQYSPQAFKF 655
            |.|||..|..|||.             |||          .:|:|...:.......:.|..|.|
Mosquito    24 GRSNGGAGADASSH-------------ERKDAADGALLEVALSREGLLDSLLVLYDECSKDAIK- 74

  Fly   656 FMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSMFV 720
            ..:::|.:.:..||.......:....:|...:         |.|
Mosquito    75 KKDKNIADFVTKYRPIIQETRERRVNVHDFDV---------KCL--------------------- 109

  Fly   721 KLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYY 785
                ||.|.||||.||::..| ..|||||.:.|..|    ....|:.||||:|...::|:..|.|
Mosquito   110 ----IGKGYFGEVHLVAERHT-KQLYAMKKMMKEAV----SSTQVRTERDIMATRRSDWITPLQY 165

  Fly   786 SFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNIL 850
            :|||..:||.||:::|||||:||:|::|:|:||||:||:||:|.|:.|:|.:|::||||||:|||
Mosquito   166 AFQDSHSLYLVMEFLPGGDLLSLMIRVGVFDEELAQFYLAELTAALHSLHTLGYVHRDIKPENIL 230

  Fly   851 IDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENGPKPTVLERRRMRDHQR 915
            :||.||:||.|||..|...                       ::.|.:.|.|
Mosquito   231 LDRFGHLKLADFGNATAIN-----------------------DDGSVSSPMP------------- 259

  Fly   916 VLAHSLVGTPNYIAPEVLE----------RSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQ 970
                  ||||:|||||:|:          .:.:...||:||:|:|.||.:..|.||...:..||.
Mosquito   260 ------VGTPDYIAPELLQTLSTISRTVNSAKHDVTCDFWSMGIIGYEFITEQTPFHGVNVNETY 318

  Fly   971 QKVINW-----EKTLHIPPQAELSREATDLIRRLCASADKRLGKSVDEVKSHDFFKGIDFADMRK 1030
            .|::..     .:.|..|....:|....||:.||..:|..|:  |..|:..|.||:.:::..:|.
Mosquito   319 SKILEHCEGRIGRKLTFPAHVSISTSYRDLLDRLVTNASNRI--SYPEIVRHPFFRDLNWDRLRY 381

  Fly  1031 QKAPYIPEIKHPTDTSNFDPVDPEKLRS---------NDSTMS--SGDDV 1069
            ...|.||.:....||||||.||....|.         |.:.|:  ||.|:
Mosquito   382 MIPPIIPTVSSDDDTSNFDDVDKTAKRKAMLGRKPTYNIARMNEFSGHDL 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	134/379 (35%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	114/315 (36%)
AgaP_AGAP006932	XP_308829.4	PKc_like	103..439	CDD:304357	136/412 (33%)
		S_TKc	104..371	CDD:214567	116/349 (33%)
		Mplasa_alph_rch	559..1257	CDD:275316
		CNH	1560..1834	CDD:279162
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920