DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and Cdc42bpb

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_006240624.1	Gene:	Cdc42bpb / 113960	RGDID:	621753	Length:	1730	Species:	Rattus norvegicus

Alignment Length:	416	Identity:	158/416 - (37%)
Similarity:	231/416 - (55%)	Gaps:	77/416 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   709 LKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILA 773
            :|..::.:..|..:|.||.||||||.:| |:..:..:||||.|.|.::|||.:.|..:.|||:|.
  Rat    66 VKDMQLHREDFEIIKVIGRGAFGEVAVV-KMKNTERIYAMKILNKWEMLKRAETACFREERDVLV 129

  Fly   774 EADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFE----EELARFYIAEVTCAVDSV 834
            ..|..|:..|:|:|||::.||.||||..||||::||.|   ||    |::|||||.|:..|:||:
  Rat   130 NGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSK---FEDKLPEDMARFYIGEMVLAIDSI 191

  Fly   835 HKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENG 899
            |::.::||||||||:|:|.:|||:|.|||.|.
  Rat   192 HQLHYVHRDIKPDNVLLDVNGHIRLADFGSCL--------------------------------- 223

  Fly   900 PKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLE-----RSGYTQLCDYWSVGVILYEMLVGQP 959
                     :|.|...|.:...||||:||:||:|:     ...|...||:||:||.:||||.|:.
  Rat   224 ---------KMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGET 279

  Fly   960 PFLANSPLETQQKVINWEKTLHIPPQ-AELSREATDLIRRLCASADKRLGKS-VDEVKSHDFFKG 1022
            ||.|.|.:||..|::|.|:....|.. .::|.||.|||:||..|.::|||:: :::.|.|.||:|
  Rat   280 PFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEG 344

  Fly  1023 IDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGDDVDQNDRTFHGF------FE 1081
            :::.::|..:|||||::..|:|||||| ||.:.|| |...:..|....     |.|.      |.
  Rat   345 LNWENIRNLEAPYIPDVSSPSDTSNFD-VDDDVLR-NIEILPPGSHTG-----FSGLHLPFIGFT 402

  Fly  1082 FTFRRFFDDK-------QPPDMTDDQ 1100
            ||....|.|:       |...:|.|:
  Rat   403 FTTESCFSDRGSLKSMIQSNTLTKDE 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	148/371 (40%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	125/311 (40%)
Cdc42bpb	XP_006240624.1	STKc_MRCK_beta	3..411	CDD:270774	154/397 (39%)
		S_TKc	76..342	CDD:214567	125/311 (40%)
		TPH	419..786	CDD:290579	3/10 (30%)
		KELK	528..606	CDD:292424
		DMPK_coil	878..939	CDD:117396
		C1	1044..1093	CDD:237996
		PH_MRCK	1103..1237	CDD:269949
		CNH	1263..1529	CDD:279162
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920