DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wts and rock2

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_004914525.1	Gene:	rock2 / 100493965	XenbaseID:	XB-GENE-959451	Length:	1399	Species:	Xenopus tropicalis

Alignment Length:	400	Identity:	147/400 - (36%)
Similarity:	223/400 - (55%)	Gaps:	66/400 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   699 LNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVA 763
            ||:.|.....:::.:|....:..:|.||.||||||.|| :...|..:||||.|.|.:::||:..|
Frog    58 LNRYEKIVREVRKLQMKAEDYDVVKVIGRGAFGEVQLV-RHKGSQKVYAMKLLSKFEMIKRSDSA 121

  Fly   764 HVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVT 828
            ....||||:|.|::.|||:|:.:|||:.:||.||:|:|||||::|:....: .|:.|:||.|||.
Frog   122 FFWEERDIMAFANSPWVVQLFCAFQDEKHLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVV 185

  Fly   829 CAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWE 893
            .|::::|.||.||||:||||:|:|:.||:||.|||.|
Frog   186 LALNAIHSMGLIHRDVKPDNMLLDKYGHLKLADFGTC---------------------------- 222

  Fly   894 EYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSG----YTQLCDYWSVGVILYEM 954
                          .:|.....|...:.||||:||:||||:..|    |.:.||:|||||.|:||
Frog   223 --------------MKMDQTGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEM 273

  Fly   955 LVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGKS-VDEVKSHD 1018
            |||..||.|:|.:.|..|:::.:.:|:.|...|:|..|.:||.......:.|||:: ::::|.|.
Frog   274 LVGDTPFYADSLVGTYSKIMDHKNSLNFPEDVEISVHAKNLICAFLTDREVRLGRNGIEDIKQHP 338

  Fly  1019 FFKG--IDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGD-DVDQNDRTFHG-- 1078
            |||.  .::.::|:..||.:||:....||||||.::.:|          || :...|.:.|.|
Frog   339 FFKNDQWNWDNIRETVAPVVPELASDIDTSNFDDIEDDK----------GDAETFPNPKAFAGNQ 393

  Fly  1079 --FFEFTFRR 1086
              |..||:.|
Frog   394 LPFIGFTYYR 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	138/368 (38%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	119/305 (39%)
rock2	XP_004914525.1	STKc_ROCK2	25..403	CDD:270771	146/398 (37%)
		S_TKc	78..340	CDD:214567	119/305 (39%)
		Smc	<432..1113	CDD:224117
		HR1_ROCK2	492..558	CDD:212028
		Rho_Binding	966..1032	CDD:286056
		PH_ROCK	1138..1242	CDD:269948
		C1	1246..1292	CDD:237996
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010