DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wts and rock1

DIOPT Version :9

Sequence 1:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	XP_021334267.1	Gene:	rock1 / 100329779	ZFINID:	ZDB-GENE-100712-2	Length:	1375	Species:	Danio rerio

Alignment Length:	396	Identity:	153/396 - (38%)
Similarity:	219/396 - (55%)	Gaps:	53/396 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   699 LNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVA 763
            |.:.:....:::..:|....:..:|.||.||||||.|| :...:..:||||.|.|.:::||:..|
Zfish    58 LKRYKDTISKIRELRMKAEDYEVVKVIGRGAFGEVQLV-RHKATRKVYAMKLLSKFEMIKRSDSA 121

  Fly   764 HVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVT 828
            ....||||:|.|::||||:|:|:|||...||.||:|:|||||::|:....: .|:.||||.|||.
Zfish   122 FFWEERDIMAFANSNWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVV 185

  Fly   829 CAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWE 893
            .|:|.:|.|||||||:||||:|:|:.||:||.|||.|
Zfish   186 LALDGIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTC---------------------------- 222

  Fly   894 EYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSG----YTQLCDYWSVGVILYEM 954
                          .:|.....|...:.||||:||:||||:..|    |.:.||:|||||.||||
Zfish   223 --------------MKMNKDGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEM 273

  Fly   955 LVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGKS-VDEVKSHD 1018
            |||..||.|:|.:.|..|::|.:..|..|..:::|::|..||.......:.|||:: |||:|.|.
Zfish   274 LVGDTPFYADSLVGTYSKIMNHKNALTFPEDSDISKDAKSLICAFLTDREVRLGRNGVDEIKRHG 338

  Fly  1019 FFKGIDFA--DMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGDDVDQNDRTFHGFFE 1081
            |||...:.  ::|:..||.:||:...|||||||  |.|:.|..:.|.........|...|.||..
Zfish   339 FFKNDQWTWENIRETAAPVVPELSCDTDTSNFD--DIEEDRGEEETFPIPKAFVGNQLPFVGFTY 401

  Fly  1082 FTFRRF 1087
            ::...|
Zfish   402 YSNNLF 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	148/367 (40%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	127/305 (42%)
rock1	XP_021334267.1	STKc_ROCK1	4..408	CDD:270772	153/396 (39%)
		SMC_N	<426..1105	CDD:330553
		PH_ROCK	1124..1230	CDD:269948
		C1	1234..1288	CDD:237996
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920