Protein Alignment zfh1 and lab

DIOPT Version :10

• Sequence 1: NP_733401.3
• Gene: zfh1 / 43650
• FlyBaseID: FBgn0004606
• Length: 1206
• Species: Drosophila melanogaster
• Sequence 2: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 793
• Identity: 147/793 - (18%)
• Similarity: 251/793 - (31%)
• Gaps: 262/793 - (33%)

  Fly   120 MSGSSRRYAKSPLASNNNSSTANA-NNNSTSSQSMNNNSELAKNHNSANKMSPMCSPGSLTPGDL 183
            |...|..|...|   :::...||| :..||::.|..|.|                        ..
  Fly     1 MMDVSSMYGNHP---HHHHPHANAYDGYSTTTASAANAS------------------------SY 38

  Fly   184 FAQLQHPPP-QLPPHLHAQFMAAAASLAMQSARTASSPSQ---QQQQQL-----QQQQQLQQQQQ 239
            ||..||.|. ||......|.:.........:...:|||..   |||.||     ...|.:||.||
  Fly    39 FAPQQHQPHLQLQQQQQHQHLQQPQQHLTYNGYESSSPGNYYPQQQAQLTPPPTSSHQVVQQHQQ 103

  Fly   240 HQMAMQQLLPPQLPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLSGAYPCMQCTASFASREQL 304
            .|.|.||.|.|     :|.:.|.||.:..::...:|.:||:.      .:|     :|.:..:..
  Fly   104 QQQAQQQQLYP-----HSHLFSPSAAEYGITTSTTTGNPGTP------LHP-----SSHSPADSY 152

  Fly   305 EQHEQLHSPCGPAAV------SNVSQTCRICHKAFANVYRLQRH--MISHDESALLRKFKCKECD 361
            .:.:.:||....|||      ||.|........|.:|..:.|:.  :||.:...:.....|....
  Fly   153 YESDSVHSYYATAAVATVAPPSNSSPITAANASATSNTQQQQQQAAIISSENGMMYTNLDCMYPT 217

  Fly   362 KAFKFKHH-----LKEHVR--IHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRA 419
            ...:...|     ::|...  :|:...|                            |:.|.:...
  Fly   218 AQAQAPVHGYAGQIEEKYAAVLHASYAP----------------------------GMVLEDQDP 254

  Fly   420 LLKRLEKSPGSASSASRRSPSDHGKGKLPEQPSLPGLPHPMSYFASDAQVQGGSAAPAPFPPFHP 484
            ::::          |::.....|.:             |....:|.||....|..|
  Fly   255 MMQQ----------ATQSQMWHHQQ-------------HLAGSYALDAMDSLGMHA--------- 287

  Fly   485 NYMNAALLAFPHNFMAAAAGLDPRVHPYSIQRLLQLSAAGQQQREEEREEQQ--KQQQHDEEETP 547
             :|:..|   ||..:...|.     :|:            |||.:.::::||  :|.||.:.::|
  Fly   288 -HMHHGL---PHGHLGNLAN-----NPH------------QQQPQVQQQQQQPHQQPQHPQNQSP 331

  Fly   548 DEPKLVMDIEEPETKEMAP------------------TPEATEAATPIKREESREASPDPESYRS 594
            ...      ::.....::|                  |..:|.|:.......::..||   ::.|
  Fly   332 AAH------QQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSP---NHSS 387

  Fly   595 SSQAIKQEQEPLNVAEERQTPVEEHAPVEHAADLRCSRCSKQF--------------NHPTEL-- 643
            |....|..|...||.:    |.....|....|.:...:.:.|.              |.|..:
  Fly   388 SIPTYKWMQLKRNVPK----PQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGG 448

  Fly   644 -----------VQHEKVLCGLIKEELEQH---FQQQQATSFALASASEEDEEDEEMDVEEEPRQE 694
                       ||:..::..........|   ......:...|:|.|.....:           .
  Fly   449 NGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTN-----------N 502

  Fly   695 SGERKVRVRTAINEEQQQQLKQHYSLNARPSRDEFRMIAARLQLDPRVVQVWFQNNRSRERK--- 756
            ||      ||....:|..:|::.:..|...:|.....||..|||:...|::||||.|.:::|
  Fly   503 SG------RTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVK 561

  Fly   757 -------MQSFQNNQAAGAAPPMPIDSQASLTREDQPLDLSVKRD-------------PLTPKSE 801
                   :.:..:.......||.        .::.||.:|.:|..             |.||.:.
  Fly   562 EGLIPADILTQHSTSVISEKPPQ--------QQQPQPPELQLKSQGSDLGGNELATGAPSTPTTA 618

  Fly   802 SSPPYIAPPSGEA 814
            .:  ..||.|.::
  Fly   619 MT--LTAPTSKQS 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zfh1	NP_733401.3	C2H2 Zn finger	291..311	CDD:275368	1/19 (5%)
		C2H2 Zn finger	326..346	CDD:275368	4/21 (19%)
		zf-H2C2_2	338..365	CDD:463886	4/28 (14%)
		zf-C2H2	355..377	CDD:395048	3/28 (11%)
		C2H2 Zn finger	357..377	CDD:275368	3/26 (12%)
		zf-H2C2_2	369..391	CDD:463886	4/28 (14%)
		Homeodomain	701..756	CDD:459649	17/54 (31%)
		C2H2 Zn finger	969..989	CDD:275368
		zf-H2C2_2	981..1006	CDD:463886
		C2H2 Zn finger	997..1017	CDD:275368
		zf-H2C2_2	1009..1034	CDD:463886
		C2H2 Zn finger	1025..1042	CDD:275368
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	17/52 (33%)