DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zfh1 and ZK686.5

DIOPT Version :9

Sequence 1:	NP_733401.3	Gene:	zfh1 / 43650	FlyBaseID:	FBgn0004606	Length:	1206	Species:	Drosophila melanogaster
Sequence 2:	NP_001023030.2	Gene:	ZK686.5 / 3565160	WormBaseID:	WBGene00022795	Length:	263	Species:	Caenorhabditis elegans

Alignment Length:	181	Identity:	36/181 - (19%)
Similarity:	73/181 - (40%)	Gaps:	17/181 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 AQFMAAAASLAMQSARTASSPSQQQQQQLQQQQQLQQQQQHQMAMQQLLPPQLPGSNSSVGSNSA 264
            :.|.:|::.:|.:..:...:.|.::....:.:::...::...:..:..:...:..:|..: .|..
Worm    90 SSFPSASSYIAAKKRKNVDNTSTRKPYSYKDRKRKNTEEIRNIKKKLFMDLGIVRTNCGI-DNEK 153

  Fly   265 YDLDLSAPRSTSSPGSTTGDLSGAYPCMQCTASFASREQLEQHEQLHSPCGPAAVSNVSQ-TCRI 328
            .|.:.:..|..:....||      | |..|..:|:|.:.|..|.        ..|.|... .|.:
Worm   154 QDREKAMKRKVTETIVTT------Y-CELCEQNFSSSKMLLLHR--------GKVHNTPYIECHL 203

  Fly   329 CHKAFANVYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRIHSG 379
            |.|.|:...:..|||.:|.........:|:.||:.||.|..|:.|..:..|
Worm   204 CMKLFSQTIQFNRHMKTHYGPNAKIYVQCELCDRQFKDKQSLRTHWDVSHG 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zfh1	NP_733401.3	C2H2 Zn finger	291..311	CDD:275368	6/19 (32%)
		C2H2 Zn finger	326..346	CDD:275368	7/19 (37%)
		zf-C2H2	355..377	CDD:278523	8/21 (38%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		zf-H2C2_2	369..391	CDD:290200	3/11 (27%)
		Homeobox	703..755	CDD:278475
		C2H2 Zn finger	969..989	CDD:275368
		zf-H2C2_2	981..1006	CDD:290200
		COG5048	992..>1045	CDD:227381
		C2H2 Zn finger	997..1017	CDD:275368
		zf-H2C2_2	1009..1034	CDD:290200
		C2H2 Zn finger	1025..1042	CDD:275368
ZK686.5	NP_001023030.2	C2H2 Zn finger	173..194	CDD:275368	6/28 (21%)
		C2H2 Zn finger	201..221	CDD:275368	7/19 (37%)
		zf-C2H2_8	<204..251	CDD:292531	15/46 (33%)
		C2H2 Zn finger	232..248	CDD:275368	7/15 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000