DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment zfh1 and tup

DIOPT Version :10

Sequence 1:NP_733401.3 Gene:zfh1 / 43650 FlyBaseID:FBgn0004606 Length:1206 Species:Drosophila melanogaster
Sequence 2:NP_476775.1 Gene:tup / 35147 FlyBaseID:FBgn0003896 Length:534 Species:Drosophila melanogaster


Alignment Length:384 Identity:93/384 - (24%)
Similarity:138/384 - (35%) Gaps:95/384 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   624 HAADLRCSRCSKQFNHPTELVQHE--KVLCGLIKEELEQHFQQQQATSFALASASEE-------- 678
            |....|||.|::|.....|....:  .:.|      .|.|...::::..:|.|:|.|        
  Fly   138 HIECFRCSACARQLLPGDEFALRDAGALYC------KEDHDVLEKSSQSSLTSSSVESNNNISSS 196

  Fly   679 ---------DEEDEEMDVEEEPRQESGERK---------------VRVRTAINEEQQQQLKQHYS 719
                     :....|:....:...|||..|               .||||.:||:|...|:..|:
  Fly   197 NNNNTNLSNNNHSSELGSMSDSGSESGSHKSIRDKRPSGPSDGKPTRVRTVLNEKQLHTLRTCYN 261

  Fly   720 LNARPSRDEFRMIAARLQLDPRVVQVWFQNNRSRER------KMQSFQNNQAA----GAAPPMPI 774
            .|.||.......:.....|.|||::|||||.|.:::      |:|..|..:..    ||...:|:
  Fly   262 ANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGRKLGYGAMQGIPM 326

  Fly   775 DSQASLTREDQPLDLSVKRDPLTPKSESSPPYIAPPSGEALNPE-----AINLSRKFSTSASMSP 834
            .: :|..|.|.||:|. ..|..|    ..||:.| .|..||:.:     |||         :.:|
  Fly   327 IA-SSPVRHDSPLNLQ-GLDVQT----YQPPWKA-LSDFALHADLDSNGAIN---------THTP 375

  Fly   835 ASISPSSAAALYFGAAPPPSPPNSQLDSTPRSGQAFPGLPPYMLPMSLPMEALFKMRPGGDFASN 899
            |.....:....|.....|..||:..  |.|..|      ||:..|..          |||  ..|
  Fly   376 AFQQLVNQMHGYDLNGMPILPPHPH--SHPAQG------PPHQHPPP----------PGG--PHN 420

  Fly   900 HALMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISH--EDEFGAGVLMPPKPRRGKAET 956
            |......:.|.  |:||..|.:........||.:::  .|:.....|.|.......|.|
  Fly   421 HQNQQPNQQPG--GSSLDSGITSHHHPDSTDSYVTYLESDDKSKLALTPSSSSSASAGT 477

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
zfh1NP_733401.3 C2H2 Zn finger 291..311 CDD:275368
C2H2 Zn finger 326..346 CDD:275368
zf-H2C2_2 338..365 CDD:463886
zf-C2H2 355..377 CDD:395048
C2H2 Zn finger 357..377 CDD:275368
zf-H2C2_2 369..391 CDD:463886
Homeodomain 701..756 CDD:459649 22/60 (37%)
C2H2 Zn finger 969..989 CDD:275368
zf-H2C2_2 981..1006 CDD:463886
C2H2 Zn finger 997..1017 CDD:275368
zf-H2C2_2 1009..1034 CDD:463886
C2H2 Zn finger 1025..1042 CDD:275368
tupNP_476775.1 LIM1_Isl 54..108 CDD:188752
LIM2_Isl 116..171 CDD:188760 9/38 (24%)
HOX 241..297 CDD:197696 22/55 (40%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.