Protein Alignment zfh1 and Vsx1

DIOPT Version :10

• Sequence 1: NP_733401.3
• Gene: zfh1 / 43650
• FlyBaseID: FBgn0004606
• Length: 1206
• Species: Drosophila melanogaster
• Sequence 2: NP_572232.2
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Alignment Length: 998
• Identity: 193/998 - (19%)
• Similarity: 279/998 - (27%)
• Gaps: 404/998 - (40%)

  Fly   191 PPQLPPHLHAQFMAAAASLAMQSARTASSPSQQQQQQLQQQQQLQQQQQHQMAMQQLLPPQLPGS 255
            |.:.||...|.....|.:.|..|........||||||.|||||||||||
  Fly    31 PSEAPPSPAATPPPTANTPANGSLSAVQQQQQQQQQQQQQQQQLQQQQQ---------------- 79

  Fly   256 NSSVGSNSAYDLDLSAPRSTSSPGSTTGDLSGAYPCMQCTASFASREQLE--QHEQLHSPCGPAA 318
                   .|.| .|...||.|.      |:|.........|:.|:..||.  .....::..|.||
  Fly    80 -------QAID-SLRESRSISP------DVSRLSAAAAAAAAAAAHCQLPVFNPANFYAAAGYAA 130

  Fly   319 VSNVSQTCRICHKAFANVYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRIHSGEKPF 383
            .::........|          .||.:...:|.||.|.........:|:.|.::|.
  Fly   131 AADPGNAAAAHH----------HHMTTLAAAAYLRGFLPPGFSTPHEFRGHFQQHF--------- 176

  Fly   384 GCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRALLKRLEKSPGSASSASRRSPS-DHGKGKL 447
                 |.:|           :::..:.|.:..::.|.....|:||...||:|....| ..|.|..
  Fly   177 -----GAQF-----------AEQAAARGQEYASSLANASGDEQSPSKNSSSSGNGGSGGSGSGSG 225

  Fly   448 PEQPSLPGLPHPMSYFASDAQVQGGS-----------------------------AAPAPFPPFH 483
            ...|:..||.|..|..||:....||:                             :..:|..|.|
  Fly   226 GGNPTSNGLGHLGSPTASNGGSGGGAGVGGSGGGSGTSGSNSSTSGNGGNGGSSGSRSSPAGPHH 290

  Fly   484 PNYMNAALLAFPHNFMAAAAGLDPRVHPYSIQRLLQLSAAGQQQREEEREEQQKQQQHDEEETPD 548
                :|||.|..|...||||     .|.::       :||...........|.....|
  Fly   291 ----SAALAAHQHAAAAAAA-----AHHHA-------AAAAAAHHAHHAHAQAHAHAH------- 332

  Fly   549 EPKLVMDIEEPETKEMAPTPEATEAATPIKREESREASPDPESYRSSSQAIKQEQEPLNVAEERQ 613
                                                                             
  Fly   333 ----------------------------------------------------------------- 332

  Fly   614 TPVEEHAPVEHAADLRCSRCSKQFNHPTELVQHEKVLCGLIKEELEQHFQQQQATSFALASASEE 678
              ...||...|||            |..                   |.....|.:|..|:....
  Fly   333 --AHVHAHAAHAA------------HAA-------------------HAHAHHAEAFLGAAGGAG 364

  Fly   679 DEEDEEM-----DVEEEP--RQESGERKVR---VRTAINEEQQQQLKQHYSLNARPSRDEFRMIA 733
            ...:..:     ||...|  ....|::|.:   .||.....|.::|::.:.....|......:::
  Fly   365 GNPNSLLAAHGGDVLVGPGGTGPGGKKKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLS 429

  Fly   734 ARLQLDPRVVQVWFQNNRSRERKMQSFQNNQAAGAAPPMPIDSQASLTREDQPLDLSVKRDPLTP 798
            .:..|....:|||:||.|::.||.:....:....|...:    ..::.|...||..::.:.  ..
  Fly   430 MKTGLAEDRIQVWYQNRRAKWRKTEKCWGHSTKMAEYGL----YGAMVRHSLPLPETIIKS--AK 488

  Fly   799 KSESSPPYIAPPSGEALNPEAINLSR----------KFSTSASMSPAS-----ISPSSAAALYFG 848
            :.||..|::.....::|  ||..|.:          ...|:.|.|..|     ||..|.:.|.|.
  Fly   489 EDESVAPWLLGMHKKSL--EAAELLKSDESDRETPTSDDTNTSYSAGSTHNSPISSFSISRLLFD 551

  Fly   849 AAPPPSPPNSQLDSTPRSGQAFPGLPPYMLPMSLPMEALFKMRPGGDFASNHALMNSIKLPDYRG 913
             ||||:           :|.|                       ||....:|
  Fly   552 -APPPA-----------AGSA-----------------------GGKGHHHH------------- 568

  Fly   914 TSLSPGGSEKRSWRDDDSRISHEDEFGAGVLMPPKPRRGKAETHGHAGDPDLPYVCDQCDKAFAK 978
                                 |..            .:|....|.||             :|.|.
  Fly   569 ---------------------HHH------------HKGHHHAHVHA-------------QAQAH 587

  Fly   979 QSSLARHKYEHSGQRPYQCIECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMN 1043
            ...|..|:.:...|:..|        :|.||      ||:.|...|..:.....|.|||.|.
  Fly   588 AHMLLHHQQQQQQQQQQQ--------QHHHH------LHAAENSLQQQQVAGTGSGSGSGSG--- 635

  Fly  1044 HRYSYCKPYREXVSDTSVPPTCQPGANPLAPPAMASNRGRRRVQVPAGNPPYTPHHQHPHHPHLA 1108
                         |.|        ||....|||                  :.|::|..|..||.
  Fly   636 -------------SGT--------GAGSTGPPA------------------HHPYNQQQHLHHLQ 661

  Fly  1109 AMAAFQQQHQ---QQQQQHQHHR 1128
            .:...|||.|   ||||||.||:
  Fly   662 QLQQQQQQQQQQAQQQQQHHHHQ 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zfh1	NP_733401.3	C2H2 Zn finger	291..311	CDD:275368	4/21 (19%)
		C2H2 Zn finger	326..346	CDD:275368	3/19 (16%)
		zf-H2C2_2	338..365	CDD:463886	6/26 (23%)
		zf-C2H2	355..377	CDD:395048	4/21 (19%)
		C2H2 Zn finger	357..377	CDD:275368	3/19 (16%)
		zf-H2C2_2	369..391	CDD:463886	3/21 (14%)
		Homeodomain	701..756	CDD:459649	12/57 (21%)
		C2H2 Zn finger	969..989	CDD:275368	4/19 (21%)
		zf-H2C2_2	981..1006	CDD:463886	4/24 (17%)
		C2H2 Zn finger	997..1017	CDD:275368	3/19 (16%)
		zf-H2C2_2	1009..1034	CDD:463886	5/24 (21%)
		C2H2 Zn finger	1025..1042	CDD:275368	5/16 (31%)
Vsx1	NP_572232.2	Homeodomain	395..452	CDD:459649	12/56 (21%)