DRSC/TRiP Functional Genomics Resources

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Protein Alignment zfh1 and HINFP

DIOPT Version :9

Sequence 1:NP_733401.3 Gene:zfh1 / 43650 FlyBaseID:FBgn0004606 Length:1206 Species:Drosophila melanogaster
Sequence 2:NP_001338886.1 Gene:HINFP / 25988 HGNCID:17850 Length:540 Species:Homo sapiens


Alignment Length:385 Identity:78/385 - (20%)
Similarity:122/385 - (31%) Gaps:121/385 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   294 CTASFASREQLEQHEQLHS--------PCGPAAVSNVS-------QT--------CRICHKAFAN 335
            ||.:|..|.:|.:|.:.|:        .||....:|..       ||        |..|.|.||.
Human   199 CTCTFKDRSKLREHLRSHTQEKVVACPTCGGMFANNTKFLDHIRRQTSLDQQHFQCSHCSKRFAT 263

  Fly   336 VYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRI-HSGEKPFGCDNCG---------- 389
            ...|:.||.:|     :..:||..||........|:.|:|. ||.::||.||.|.          
Human   264 ERLLRDHMRNH-----VNHYKCPLCDMTCPLPSSLRNHMRFRHSEDRPFKCDCCDYSCKNLIDLQ 323

  Fly   390 --------------------------------KRFSHSGS----FSSHMTSKKCISMGLKLNNNR 418
                                            .|..|.|.    :..|:.. ||.:.|   ||..
Human   324 KHLDTHSEEPAYRCDFENCTFSARSLCSIKSHYRKVHEGDSEPRYKCHVCD-KCFTRG---NNLT 384

  Fly   419 ALLKRLEKSPGSASSASRRSPSDHGKGKLPEQPSLPGLPHPMSYFASDAQVQGGSAAPAPFPPFH 483
            ..|::..:.         :.||.|.:.:..|        |...|.    ::|        ...:.
Human   385 VHLRKKHQF---------KWPSGHPRFRYKE--------HEDGYM----RLQ--------LVRYE 420

  Fly   484 PNYMNAALLAFPHNFMAAAAGLDPRVHPYSIQRLLQLSAAGQQQREEEREEQQKQQQHDEEETPD 548
            ...:...||..|..    .:||...::..|:|.::..:..|:..|:||.||.:..:......:.|
Human   421 SVELTQQLLRQPQE----GSGLGTSLNESSLQGIILETVPGEPGRKEEEEEGKGSEGTALSASQD 481

  Fly   549 EPKLVMDIEEPETKEMAPTPEATEAATPIKREESREASPDPE----SYRSSSQAIKQEQE 604
            .|..|:.:......:     ...|....:..|...|..|.||    ......|.|.:|.|
Human   482 NPSSVIHVVNQTNAQ-----GQQEIVYYVLSEAPGEPPPAPEPPSGGIMEKLQGIAEEPE 536

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
zfh1NP_733401.3 C2H2 Zn finger 291..311 CDD:275368 6/16 (38%)
C2H2 Zn finger 326..346 CDD:275368 8/19 (42%)
zf-C2H2 355..377 CDD:278523 7/22 (32%)
C2H2 Zn finger 357..377 CDD:275368 6/20 (30%)
zf-H2C2_2 369..391 CDD:290200 10/64 (16%)
Homeobox 703..755 CDD:278475
C2H2 Zn finger 969..989 CDD:275368
zf-H2C2_2 981..1006 CDD:290200
COG5048 992..>1045 CDD:227381
C2H2 Zn finger 997..1017 CDD:275368
zf-H2C2_2 1009..1034 CDD:290200
C2H2 Zn finger 1025..1042 CDD:275368
HINFPNP_001338886.1 COG5236 <194..>326 CDD:227561 35/131 (27%)
C2H2 Zn finger 197..216 CDD:275368 6/16 (38%)
C2H2 Zn finger 224..246 CDD:275368 4/21 (19%)
C2H2 Zn finger 254..274 CDD:275368 8/19 (42%)
C2H2 Zn finger 280..301 CDD:275368 6/20 (30%)
C2H2 Zn finger 309..329 CDD:275368 3/19 (16%)
C2H2 Zn finger 337..360 CDD:275368 1/22 (5%)
C2H2 Zn finger 370..388 CDD:275368 6/21 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165160405
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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