DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Npc2h and heh-1

DIOPT Version :9

Sequence 1:	NP_001247376.1	Gene:	Npc2h / 43649	FlyBaseID:	FBgn0039801	Length:	157	Species:	Drosophila melanogaster
Sequence 2:	NP_001379800.1	Gene:	heh-1 / 175426	WormBaseID:	WBGene00006452	Length:	154	Species:	Caenorhabditis elegans

Alignment Length:	161	Identity:	45/161 - (27%)
Similarity:	64/161 - (39%)	Gaps:	27/161 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VAFALVLSSVSAEI--VNFQTCEDSVDSCSISQVRVTPC--PEANANAACHIRRRHRFTMSFDFT 70
            |.|..:|...:||.  :.::.|:   ...::|||:...|  ...:....|..::..|..:...|.
Worm     4 VIFLALLGLAAAEFIEIGYKVCK---SDGTVSQVKADGCELTVKDGKKVCLFKKGSRPIIQIAFK 65

  Fly    71 PHFDADTLVASLGWAK---SENVELPLLTMDQEACKY-TTCPVRSGVTQTY------TNNMPADA 125
            |..|.|.|..|:. ||   |..|:.|....|  ||.| ..|||.:|..|.:      |.|.||.
Worm    66 PSKDTDKLKTSVR-AKVGGSAMVDFPQTNSD--ACTYGVKCPVSAGENQIFEQSISITENHPAG- 126

  Fly   126 RFPLSPYTIRWALKDPVSQKRCC--FTIDIK 154
                ....:.|.|..|.|.|..|  |..:||
Worm   127 ----EVIQVNWQLTRPDSGKEVCIIFLAEIK 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Npc2h	NP_001247376.1	Npc2_like	26..153	CDD:238458	38/140 (27%)
heh-1	NP_001379800.1	Npc2_like	22..150	CDD:238458	38/138 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11306
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010