Protein Alignment CG15543 and AK8

DIOPT Version :10

• Sequence 1: NP_651822.1
• Gene: CG15543 / 43647
• FlyBaseID: FBgn0039799
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: XP_005272226.1
• Gene: AK8 / 158067
• HGNCID: 26526
• Length: 491
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 71/290 - (24%)
• Similarity: 119/290 - (41%)
• Gaps: 57/290 - (19%)

  Fly    30 EVMSRL-----LAEISVADGVTDVRRWMGENITRIGVEIYTK----------SMDAFHRG---VR 76
            |:.:||     ::|:..|..:.:..|    ||.|: :..|.|          .:|.|::.   |:
Human   211 EIQNRLMVPEDISELETAQKLLEYHR----NIVRV-IPSYPKILKVISADQPCVDVFYQALTYVQ 270

  Fly    77 GDFYQLPRSFYHRIVLHGKPGSGRRSLAYVLAQRWNLLILDADVLAYHSINKQDQDEPSRLLQEA 141
            .: ::....|..|::|.|..|||:...|.:|||::.|:.:....|...::  .|:.....|:|..
Human   271 SN-HRTNAPFTPRVLLLGPVGSGKSLQAALLAQKYRLVNVCCGQLLKEAV--ADRTTFGELIQPF 332

  Fly   142 IEKDCVYKRSQAVGNLIENRLLQEDALHRGWILINYPNNKCEAEELFEGFTVPPNRFVFLQID-- 204
            .||:.....|..: .::..||.|:|.:.:||:|...|.:..:| .|.......|||..||.:.
Human   333 FEKEMAVPDSLLM-KVLSQRLDQQDCIQKGWVLHGVPRDLDQA-HLLNRLGYNPNRVFFLNVPFD 395

  Fly   205 ---ERLARMRI---------LLNSYSPGPQAHVSFVDRQMAQFRKSEPALSSYLSQRR----EVV 253
               |||...||         |:  |.|.|...:.....|..:..:.:..|...|..|.    |.:
Human   396 SIMERLTLRRIDPVTGERYHLM--YKPPPTMEIQARLLQNPKDAEEQVKLKMDLFYRNSADLEQL 458

  Fly   254 Y---------VDASPCFEQVKCGIISELTK 274
            |         .|....||.::.|||:.|.|
Human   459 YGSAITLNGDQDPYTVFEYIESGIINPLPK 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15543	NP_651822.1	COG0645	90..235	CDD:440410	42/158 (27%)
AK8	XP_005272226.1	DD_AK8	9..65	CDD:438548
		ADK	71..261	CDD:238713	11/54 (20%)
		ADK	282..474	CDD:238713	49/197 (25%)