Protein Alignment CG11313 and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 89/268 - (33%)
• Similarity: 119/268 - (44%)
• Gaps: 34/268 - (12%)

  Fly   105 SICGGDIAYNQITKGNETVLTEFAWM--VLLEYRPHDGQQLRTYCAGSLINNRYVVTAAHCVSAA 167
            |.||.....::|..|.......:.|.  |.|.:| |.       |.||::..|:|||||||:.:.
Human   207 SECGARPLASRIVGGQSVAPGRWPWQASVALGFR-HT-------CGGSVLAPRWVVTAAHCMHSF 263

  Fly   168 TRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIA-VEEIRIHESFGTRLFWNDIALIRL 231
            ..||..  |:||...|..|  |||          .|.|.| ||.|..|..:..:....|:||:||
Human   264 RLARLS--SWRVHAGLVSH--SAV----------RPHQGALVERIIPHPLYSAQNHDYDVALLRL 314

  Fly   232 AREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTLTSE--SSPVKMKLRVTYVEPGLCRRK 294
            ...:.:|.::..||||:..  |::..|....|:|||.|..|.  ||.:.....|......||...
Human   315 QTALNFSDTVGAVCLPAKE--QHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSS 377

  Fly   295 YASIVVLGDSHLCA---EGRSRGDSCDGDSGGPLMAFHEGVWVLGGIVSFGLNCGSRFWPAVYTN 356
            ......|....|||   :||:  |:|.|||||||:......|.|.|:||:|..|.....|.||..
Human   378 CVYSGALTPRMLCAGYLDGRA--DACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAK 440

  Fly   357 VLSYETWI 364
            |..:..||
Human   441 VAEFLDWI 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440
		Tryp_SPc	116..367	CDD:238113	86/257 (33%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	3/5 (60%)
		Tryp_SPc	217..448	CDD:214473	84/256 (33%)