DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11313 and prss60.1

DIOPT Version :9

Sequence 1:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	292	Identity:	91/292 - (31%)
Similarity:	135/292 - (46%)	Gaps:	58/292 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 HSTLLPDRSICGGDIAYNQITKGNETVLTEFAWMVLLEYRPHDGQQLRTYCAGSLINNRYVVTAA 161
            ||.|    ::||.....|:|..|.......:.|.|.|....:.|.    :|.|||||:.:|:|||
Zfish    19 HSQL----NVCGLAPLNNRIVGGVNAFDGSWPWQVSLHSPIYGGH----FCGGSLINSEWVLTAA 75

  Fly   162 HCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDI 226
            ||:...|.:       .:.|.||: .|...|:...       :...|..|.:|.|:......|||
Zfish    76 HCLPRITTS-------SLLVFLGK-TTQQGVNTYE-------INRTVSVITVHPSYNNLTNENDI 125

  Fly   227 ALIRLAREVAYSPSIRPVCLPSTVGLQN--WQSGQAFTVAGWGRTLTSESSPVKMKLRVTYVEPG 289
            ||:.|:..|.:|..||||||.:    ||  :.:|.:..:.|||          .::|.|....||
Zfish   126 ALLHLSSAVTFSNYIRPVCLAA----QNSVFPNGTSSWITGWG----------NIQLGVNLPAPG 176

  Fly   290 LCRRKYASIV-------VLG-----DSHLCAEGRSRG--DSCDGDSGGPLMAFHEGVWVLGGIVS 340
            :.:.....:|       :||     ::.:|| |..:|  |:|.||||||:::....|||..||.|
Zfish   177 ILQETMIPVVPNDQCNALLGSGSVTNNMICA-GLLQGGRDTCQGDSGGPMVSKQCLVWVQSGITS 240

  Fly   341 FGLNCGSRFWPAVYTNVLSYETW----ITQNI 368
            :|..|...:.|.|||.|..|::|    |.||:
Zfish   241 WGYGCADPYSPGVYTRVSQYQSWINSIIVQNL 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:288855
		Tryp_SPc	116..367	CDD:238113	83/270 (31%)
		Tryp_SPc	116..364	CDD:214473	82/267 (31%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	81/264 (31%)
		Tryp_SPc	34..267	CDD:238113	82/266 (31%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587334
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840