DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11313 and gzma

DIOPT Version :9

Sequence 1:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	XP_001335166.1	Gene:	gzma / 795070	ZFINID:	ZDB-GENE-091204-156	Length:	257	Species:	Danio rerio

Alignment Length:	277	Identity:	85/277 - (30%)
Similarity:	120/277 - (43%)	Gaps:	54/277 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 TLLPDRSICGGDIAYNQITKGNETVLTEFAWMVLLEYRPHDGQQLRTYCAGSLINNRYVVTAAHC 163
            |:..|.||.||           :.|....:|||.::...:.      .|.|.||:..:|:|||||
Zfish    21 TVCSDVSIVGG-----------KDVKKALSWMVSIQVNQNH------KCGGILIHKEWVLTAAHC 68

  Fly   164 VSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDIAL 228
                    |.|....|:|.:|..:.|           ....:||:....|.|:|..:...:||.|
Zfish    69 --------KEDSYSSVTVLIGSLSLS-----------KGSQRIAIHNYEIPETFNKKTKKDDIML 114

  Fly   229 IRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRT--LTSESSPVKMKLRVTYVEPGLC 291
            |||:::|    ..:|..:|...  ::.|.|....|.|||.|  ...::|.....|.|..|:...|
Zfish   115 IRLSKKV----KAKPYKIPKKE--KDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQC 173

  Fly   292 RRKYASIVVLGDSHLCAEG--RSRGDSCDGDSGGPLMAFHEGVWVLGGIVSFGLNCGSRFWPAVY 354
            .|.|....|:....|||..  :.|| :|.|||||||......|.||.|  |.|  ||....|.||
Zfish   174 NRYYNRNPVITKDMLCAGNTQQHRG-TCLGDSGGPLECEKNLVGVLSG--SHG--CGDPKKPTVY 233

  Fly   355 TNVLS--YETWITQNIR 369
            | :||  :.|||.:.::
Zfish   234 T-LLSKRHITWINKILK 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:288855
		Tryp_SPc	116..367	CDD:238113	79/256 (31%)
		Tryp_SPc	116..364	CDD:214473	77/253 (30%)
gzma	XP_001335166.1	Tryp_SPc	28..247	CDD:238113	82/266 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587303
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930