Protein Alignment CG11313 and TMPRSS2

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001128571.1
• Gene: TMPRSS2 / 7113
• HGNCID: 11876
• Length: 529
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 84/322 - (26%)
• Similarity: 143/322 - (44%)
• Gaps: 44/322 - (13%)

  Fly    63 SRCLVSDQSDLPFVCCTPDTDYNTTRARPN--DEVIHSTLLPDRSI-------CGGDI---AYNQ 115
            |:.:|.|.....|:      ..||:....:  .::.||.....:::       ||.::   ..::
Human   234 SQGIVDDSGSTSFM------KLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSR 292

  Fly   116 ITKGNETVLTEFAWMVLLEYRPHDGQQLRTYCAGSLINNRYVVTAAHCVSAATRARKGDVSFRVS 180
            |..|...:...:.|.|.|..     |.:.. |.||:|...::|||||||.....
Human   293 IVGGESALPGAWPWQVSLHV-----QNVHV-CGGSIITPEWIVTAAHCVEKPLN----------- 340

  Fly   181 VRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDIALIRLAREVAYSPSIRPVC 245
               ...:.:|....|....:.......||::..|.::.::...|||||::|.:.:.::..::|||
Human   341 ---NPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVC 402

  Fly   246 LPSTVGLQNWQSGQAFTVAGWGRT-LTSESSPVKMKLRVTYVEPGLCRRKYASIVVLGDSHLCAE 309
            ||:. |:. .|..|...::|||.| ...::|.|....:|..:|...|..:|....::..:.:||
Human   403 LPNP-GMM-LQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICA- 464

  Fly   310 GRSRG--DSCDGDSGGPLMAFHEGVWVLGGIVSFGLNCGSRFWPAVYTNVLSYETWITQNIR 369
            |..:|  |||.|||||||:.....:|.|.|..|:|..|...:.|.||.||:.:..||.:.:|
Human   465 GFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMR 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440	4/14 (29%)
		Tryp_SPc	116..367	CDD:238113	73/253 (29%)
TMPRSS2	NP_001128571.1	LDLa	150..185	CDD:238060
		SRCR_2	190..283	CDD:464747	9/54 (17%)
		Tryp_SPc	293..524	CDD:238113	73/253 (29%)