Protein Alignment CG11313 and TMPRSS3

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_076927.1
• Gene: TMPRSS3 / 64699
• HGNCID: 11877
• Length: 454
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 91/296 - (30%)
• Similarity: 144/296 - (48%)
• Gaps: 42/296 - (14%)

  Fly    91 PNDEVI---HSTLLPDR-----------SICGGDIAY-NQITKGNETVLTEFAWMVLLEYRPHDG 140
            |:|:|.   ||..:.:.           :.||....| ::|..||.::|:::.|...|:::   |
Human   177 PDDKVTALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQ---G 238

  Fly   141 QQLRTYCAGSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQ 205
            ..|   |.||:|...:::||||||......:    |:.:.|.|        |..|:.   |.|..
Human   239 YHL---CGGSVITPLWIITAAHCVYDLYLPK----SWTIQVGL--------VSLLDN---PAPSH 285

  Fly   206 IAVEEIRIHESFGTRLFWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTL 270
            : ||:|..|..:..:...|||||::||..:.::..|:|||||::.  :|:..|:....:|||.|.
Human   286 L-VEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSE--ENFPDGKVCWTSGWGATE 347

  Fly   271 --TSESSPVKMKLRVTYVEPGLCRRKYASIVVLGDSHLCAEGRSRG-DSCDGDSGGPLMAFHEGV 332
              ..::|||.....|..:...:|..:.....::..|.|||...:.| |||.|||||||:.....:
Human   348 DGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRL 412

  Fly   333 WVLGGIVSFGLNCGSRFWPAVYTNVLSYETWITQNI 368
            |.|.|..|||:.|.....|.|||.|.|:..||.:.:
Human   413 WKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQM 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440
		Tryp_SPc	116..367	CDD:238113	83/253 (33%)
TMPRSS3	NP_076927.1	LDLa	74..107	CDD:238060
		SRCR_2	112..210	CDD:464747	7/32 (22%)
		Tryp_SPc	216..444	CDD:214473	81/251 (32%)