DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11313 and si:dkeyp-93a5.3

DIOPT Version :9

Sequence 1:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	XP_021326347.1	Gene:	si:dkeyp-93a5.3 / 571565	ZFINID:	ZDB-GENE-131127-100	Length:	328	Species:	Danio rerio

Alignment Length:	302	Identity:	94/302 - (31%)
Similarity:	126/302 - (41%)	Gaps:	73/302 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 RPNDEVIHSTLLPDRSICGGDIAYNQITKGNETVLTEFAWMVLLEYR-PHDGQQLRTYCAGSLIN 153
            |||     .||.|  .|.||..|    |.|      .:.|||.|:.| .|       :|.|||||
Zfish    27 RPN-----PTLNP--RIVGGVNA----THG------AWPWMVSLQGRYGH-------FCGGSLIN 67

  Fly   154 NRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFG 218
            |::|:|||||:...|.:       .:.|.||:.. |.|.|.       ..:...:..|..|.|:.
Zfish    68 NQWVLTAAHCIVDQTPS-------SIIVYLGKWR-SYVADV-------NSISRTIRHIIPHPSYS 117

  Fly   219 TRLFWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWG----------RTLTSE 273
            .....|||||::|...|.|:..|:|:||...  ..|:..|....|||||          |..|:.
Zfish   118 NITKDNDIALLQLTSTVQYTDYIKPICLADE--NSNFPRGTNSWVAGWGDIGVLGTGGIRGRTTV 180

  Fly   274 SSPVKMKLRVTYVEPGLCRRKYASIVVLGDSH-----------LCAEGRSRGDSC-DGDSGGPLM 326
            |.|:.        .||:.:.....:....|.:           :||..|..|.:. .||||||||
Zfish   181 SVPLP--------HPGILQEAELKVYSNADCNNICHGRITPNMICAGTRPGGKATFSGDSGGPLM 237

  Fly   327 AFHEGVWVLGGIVSFGLNCGSRFWPAVYTNVLSYETWITQNI 368
            . ...|||..|::|.|..|.....|.|:..|..|:.|||.|:
Zfish   238 T-KCSVWVQAGVLSHGYGCAQPNLPEVFIRVSEYKQWITGNV 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:288855
		Tryp_SPc	116..367	CDD:238113	83/273 (30%)
		Tryp_SPc	116..364	CDD:214473	80/270 (30%)
si:dkeyp-93a5.3	XP_021326347.1	Tryp_SPc	36..274	CDD:238113	84/280 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910