Protein Alignment CG11313 and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 108/420 - (25%)
• Similarity: 170/420 - (40%)
• Gaps: 92/420 - (21%)

  Fly     4 IAAVLLCLLIIRTAHGQ-YVSCRNPNQ---RTGYC---VNIPL------CV------PLNSV-LA 48
            :|::::.:::|:....: |..|..|..   |...|   ::.||      ||      |..:| |:
Human    43 LASIIIVVVLIKVILDKYYFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLS 107

  Fly    49 KSNPT----------------DSEMRFIRESRCLVSDQSDLP---FVCCTPDTDYNTTRARPNDE 94
            |...|                |:....:.|:.|.....|..|   .|...||.|.:......|.:
Human   108 KDRSTLQVLDSATGNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQ 172

  Fly    95 ----------VIHSTLLPDRSI-CGGDIAYNQITKGNETVLTEFAWMVLLEYRPHDGQQLRTYCA 148
                      .:..:|:....: ||..:...::....|..:..:.|.|.::|   |.|.:   |.
Human   173 ELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQY---DKQHV---CG 231

  Fly   149 GSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRI 213
            ||:::..:|:|||||.      ||....|...||.|.....:         .|   .:||.:|.|
Human   232 GSILDPHWVLTAAHCF------RKHTDVFNWKVRAGSDKLGS---------FP---SLAVAKIII 278

  Fly   214 HESFGTRLFWNDIALIRLAREVAYSPSIRPVCLP-----STVGLQNWQSGQAFTVAGWGRTLTS- 272
            .|........|||||::|...:.:|.::||:|||     .|.....|       :.|||.|..:
Human   279 IEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLW-------IIGWGFTKQNG 336

  Fly   273 -ESSPVKMKLRVTYVEPGLCRRKYASIVVLGDSHLCAEGRSRG--DSCDGDSGGPLMAFHEGVWV 334
             :.|.:.::..|..::...|....|....:.:..:|| |...|  |:|.|||||||| :....|.
Human   337 GKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCA-GIPEGGVDTCQGDSGGPLM-YQSDQWH 399

  Fly   335 LGGIVSFGLNCGSRFWPAVYTNVLSYETWI 364
            :.||||:|..||....|.|||.|.:|..||
Human   400 VVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440	19/91 (21%)
		Tryp_SPc	116..367	CDD:238113	79/258 (31%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060	7/33 (21%)
		SRCR_2	108..197	CDD:470597	13/88 (15%)
		Tryp_SPc	204..429	CDD:214473	77/257 (30%)