Protein Alignment CG11313 and KLK7

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 83/288 - (28%)
• Similarity: 123/288 - (42%)
• Gaps: 57/288 - (19%)

  Fly    98 STLLPDRSI--------CGGDIAYNQITKGNETVLTEFAWMVLLEYRPHDGQQLRTYCAGSLINN 154
            |.|||.:.:        .|.:...::|..|.........|.|.|    ..|.||  :|.|.|:|.
Human     4 SLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVAL----LSGNQL--HCGGVLVNE 62

  Fly   155 RYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFGT 219
            |:|:|||||                  ::.|:......|.|..|   ...:|...:...|..:.|
Human    63 RWVLTAAHC------------------KMNEYTVHLGSDTLGDR---RAQRIKASKSFRHPGYST 106

  Fly   220 RLFWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTLT------SESSPVK 278
            :...||:.|::|..:...|..::.|.|||...    ..|...||:|||.|.:      |:...|.
Human   107 QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE----PPGTTCTVSGWGTTTSPDVTFPSDLMCVD 167

  Fly   279 MKLRVTYVEPGLCRRKYASIVVLGDSHLCAE-GRSRGDSCDGDSGGPLMAFHEGVWVLGGIVSFG 342
            :||    :.|..|.:.|..:  |.:|.|||. ..|:.::|:|||||||:.  .|  .|.|:||:|
Human   168 VKL----ISPQDCTKVYKDL--LENSMLCAGIPDSKKNACNGDSGGPLVC--RG--TLQGLVSWG 222

  Fly   343 -LNCGSRFWPAVYTNVLSYETWITQNIR 369
             ..||....|.|||.|..:..||...::
Human   223 TFPCGQPNDPGVYTQVCKFTKWINDTMK 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440
		Tryp_SPc	116..367	CDD:238113	78/258 (30%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	76/256 (30%)