Protein Alignment CG11313 and PRSS2

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 76/231 - (32%)
• Similarity: 115/231 - (49%)
• Gaps: 28/231 - (12%)

  Fly   146 YCAGSLINNRYVVTAAHCVSAATRAR---KGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIA 207
            :|.||||:.::||:|.||..:|..::   :|....|:.|||||||    ::.|.|.   |....|
Human    47 FCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHN----IEVLEGN---EQFINA 104

  Fly   208 VEEIRIHESFGTRLFWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTLTS 272
            .:.|| |..:.:|...|||.||:|:.....:..:..:.||:...    .:|....::|||.||:|
Human   105 AKIIR-HPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPP----AAGTESLISGWGNTLSS 164

  Fly   273 ESS-PVKMK-LRVTYVEPGLCRRKYASIVVLGDSHLCA---EGRSRGDSCDGDSGGPLMAFHEGV 332
            .:. |.::: |....:....|...|...:.  ::..|.   ||..  |||.||||||:::..|
Human   165 GADYPDELQCLDAPVLSQAECEASYPGKIT--NNMFCVGFLEGGK--DSCQGDSGGPVVSNGE-- 223

  Fly   333 WVLGGIVSFGLNCGSRFWPAVYTNVLSYETWITQNI 368
              |.||||:|..|..:..|.|||.|.:|..||...|
Human   224 --LQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440
		Tryp_SPc	116..367	CDD:238113	75/228 (33%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	75/228 (33%)