Protein Alignment CG11313 and KLK14

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 73/264 - (27%)
• Similarity: 122/264 - (46%)
• Gaps: 45/264 - (17%)

  Fly   114 NQITKGNETVLTEFAWMVLLEYRPHDGQQLRTYCAGSLINNRYVVTAAHCVSAATRARKGDVSFR 178
            |:|..|:....:...|...|    ..|.:.|..|.|:|::.::|:|||||....
Human    23 NKIIGGHTCTRSSQPWQAAL----LAGPRRRFLCGGALLSGQWVITAAHCGRPI----------- 72

  Fly   179 VSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIR--IHESFGTRLFWNDIALIRLAREVAYSPSI 241
            :.|.||:||....          |..|..:..:|  .|.::.:|...||:.|::|.:......::
Human    73 LQVALGKHNLRRW----------EATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAV 127

  Fly   242 RPVCLPSTVGLQNWQSGQAFTVAGWGRTLTSESS--PVKMKLRVTYVEPG-LCRRKYASIVVLGD 303
            ||:.:.....    ..|.:..|:||| |::|..:  |..::.....:.|. :|::.|...:..|
Human   128 RPIEVTQACA----SPGTSCRVSGWG-TISSPIARYPASLQCVNINISPDEVCQKAYPRTITPG- 186

  Fly   304 SHLCAEGRSRG--DSCDGDSGGPLMAFHEGVWVLGGIVSFGL-NCGSRFWPAVYTNVLSYETWIT 365
             .:|| |..:|  |||.|||||||:...:    |.|:||:|: .|....:|.||||:..|.:||.
Human   187 -MVCA-GVPQGGKDSCQGDSGGPLVCRGQ----LQGLVSWGMERCALPGYPGVYTNLCKYRSWIE 245

  Fly   366 QNIR 369
            :.:|
Human   246 ETMR 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440
		Tryp_SPc	116..367	CDD:238113	71/258 (28%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	71/258 (28%)