Protein Alignment CG11313 and KLK2

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 68/243 - (27%)
• Similarity: 104/243 - (42%)
• Gaps: 54/243 - (22%)

  Fly   146 YCAGSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEE 210
            :|.|.|::.::|:|||||:...::           |.||.||            |.||.... :.
Human    49 HCGGVLVHPQWVLTAAHCLKKNSQ-----------VWLGRHN------------LFEPEDTG-QR 89

  Fly   211 IRIHESFGTRLF----------------WNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQ 259
            :.:..||...|:                .:|:.|:||:.....:..::.:.||:    |....|.
Human    90 VPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT----QEPALGT 150

  Fly   260 AFTVAGWGRTLTSE-SSPVKMK-LRVTYVEPGLCRRKYASIVVLGDSHLCAEGRSRG-DSCDGDS 321
            ....:|||.....| ..|..:: :.:..:...:|.|.|:..|.  :..|||...:.| |:|.|||
Human   151 TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT--EFMLCAGLWTGGKDTCGGDS 213

  Fly   322 GGPLMAFHEGVWVLGGIVSFGLN-CGSRFWPAVYTNVLSYETWITQNI 368
            ||||:.  .|  ||.||.|:|.. |.....|||||.|:.|..||...|
Human   214 GGPLVC--NG--VLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440
		Tryp_SPc	116..367	CDD:238113	67/240 (28%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	67/240 (28%)