Protein Alignment CG11313 and KLK1

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 69/243 - (28%)
• Similarity: 103/243 - (42%)
• Gaps: 55/243 - (22%)

  Fly   147 CAGSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEI 211
            |.|.|::.::|:|||||:|.           ...:.||.||   :.|..|....     :.|.|.
Human    50 CGGILVHRQWVLTAAHCISD-----------NYQLWLGRHN---LFDDENTAQF-----VHVSES 95

  Fly   212 RIHESFGTRLFWN-----------DIALIRLAREV-AYSPSIRPVCLPSTVGLQNWQSGQAFTVA 264
            ..|..|...|..|           |:.|:||.... ..:.:::.|.||:    :..:.|.....:
Human    96 FPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPT----EEPEVGSTCLAS 156

  Fly   265 GWGR------TLTSESSPVKMKLRVTYVEPGLCRRKYASIVVLGDSHLCAEGRSRG--DSCDGDS 321
            |||.      :...:...|.:|:    :....|::.:...|.  |..||. |...|  |:|.|||
Human   157 GWGSIEPENFSFPDDLQCVDLKI----LPNDECKKAHVQKVT--DFMLCV-GHLEGGKDTCVGDS 214

  Fly   322 GGPLMAFHEGVWVLGGIVSFG-LNCGSRFWPAVYTNVLSYETWITQNI 368
            |||||.  :|  ||.|:.|:| :.||:...|:|...||||..||...|
Human   215 GGPLMC--DG--VLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440
		Tryp_SPc	116..367	CDD:238113	68/240 (28%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	68/240 (28%)